Copper supported modified magnetic carrageenan as a bio-based catalyst for the synthesis of novel scaffolds bearing the 1,2,3-triazole unit through the click reaction

被引：6

作者：

Khaleghi, Nima ^{[1
]}

Esmkhani, Maryam ^{[2
]}

Noori, Milad ^{[2
]}

Dastyafteh, Navid ^{[2
]}

Ghomi, Minoo Khalili ^{[1
]}

Mahdavi, Mohammad ^{[1
]}

Sayahi, Mohammad Hosein ^{[3
]}

Javanshir, Shahrzad ^{[2
]}

机构：

[1] Univ Tehran Med Sci, Endocrinol & Metab Clin Sci Inst, Endocrinol & Metab Res Ctr, Tehran, Iran

[2] Iran Univ Sci & Technol, Dept Chem, Pharmaceut & Heterocycl Cpds Res Lab, Tehran 1684613314, Iran

[3] Payame Noor Univ, Dept Chem, Tehran, Iran

来源：

NANOSCALE ADVANCES | 2024年 / 6卷 / 09期

基金：

英国科研创新办公室;

关键词：

DERIVATIVES; DESIGN; FOOD;

D O I：

10.1039/d4na00022f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The ongoing work delineates the design of a novel library of 1,2,3-triazole-attached phenylacetamides through molecular hybridization of propargyl and phenylacetamide derivatives. Copper-supported modified magnetic carrageenan serves as a green heterogeneous catalyst, ensuring high yield, efficient reaction times, high atom economy, utilization of an environmentally friendly catalyst from a natural source, and a straightforward workup procedure. The successful synthesis of the catalyst is confirmed and evaluated using various analytical techniques, while the synthetic compounds are characterized through 1H NMR and 13C NMR. Design of a novel library of new 1,2,3-triazole-attached phenyl acetamides via molecular hybridization of propargyl and phenylacetamide derivatives using copper-supported modified magnetic carrageenan as a green heterogeneous catalyst.

引用

页码：2337 / 2349

页数：13

共 50 条

[41] Design, synthesis and biological evaluation of 1,2,3-triazole based 2-aminobenzimidazoles as novel inhibitors of LasR dependent quorum sensing in Pseudomonas aeruginosa
Srinivasarao, Singireddi
Nandikolla, Adinarayana
Nizalapur, Shashidhar
Yu, Tsz Tin
Pulya, Sravani
Ghosh, Balaram
Murugesan, Sankaranarayanan
Kumar, Naresh
Sekhar, Kondapalli Venkata Gowri Chandra
[J]. RSC ADVANCES, 2019, 9 (50) : 29273 - 29292
[42] Synthesis of novel 2-mercapto benzothiazole and 1,2,3-triazole based bis-heterocycles: Their anti-inflammatory and anti-nociceptive activities
Shafi, Syed
Alam, Mohammad Mahboob
Mulakayala, Naveen
Mulakayala, Chaitanya
Vanaja, G.
Kalle, Arunasree M.
Pallu, Reddanna
Alam, M. S.
[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 49 : 324 - 333
[43] Regioselective synthesis and DFT computational studies of novel β-hydroxy-1,4-disubstituted-1,2,3-triazole-based benzodiazepinediones using click cycloaddition reaction
Paghandeh, Hossein
Foumeshi, Maryam Khalili
Saeidian, Hamid
[J]. STRUCTURAL CHEMISTRY, 2021, 32 (03) : 1279 - 1287
[44] Synthesis of ciprofloxacin-linked 1,2,3-triazole conjugates as potent antibacterial agents using click chemistry: exploring their function as DNA gyrase inhibitors via in silico- and in vitro-based studies
Patel, Upendra Kumar
Tiwari, Punit
Tilak, Ragini
Joshi, Gaurav
Kumar, Roshan
Agarwal, Alka
[J]. RSC ADVANCES, 2024, 14 (24) : 17051 - 17070
[45] Design, Synthesis, Anticancer Activity and Molecular Docking of New 1,2,3-Triazole-Based Glycosides Bearing 1,3,4-Thiadiazolyl, Indolyl and Arylacetamide Scaffolds
Elganzory, Hussein H.
Alminderej, Fahad M.
El-Bayaa, Mohamed N.
Awad, Hanem M.
Nossier, Eman S.
El-Sayed, Wael A.
[J]. MOLECULES, 2022, 27 (20):
[46] Synthesis of novel 1,2,3-triazole based benzoxazolinones: Their TNF-α based molecular docking with in-vivo anti-inflammatory, antinociceptive activities and ulcerogenic risk evaluation
Haider, Saqlain
Alam, M. Sarwar
Hamid, Hinna
Shafi, Syed
Nargotra, Amit
Mahajan, Priya
Nazreen, Syed
Kalle, Arunasree M.
Kharbanda, Chetna
Ali, Yakub
Alam, Aftab
Panda, Amulya K.
[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 70 : 579 - 588
[47] Synthesis and Identification of Novel Potential Thiadiazole Based Molecules Containing 1,2,3-triazole Moiety Against COVID-19 Main Protease Through Structure-Guided Virtual Screening Approach
Rashdan, Huda R. M.
Abdelmonsef, Aboubakr H.
Abou-Krisha, Mortaga M.
Yousef, Tarek A.
[J]. BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY, 2022, 12 (06): : 8258 - 8270
[48] Synthesis of novel 1,2,3-triazole based acridine and benzothiazole scaffold N-glycosides with anti-proliferative activity, docking studies, and comparative computational studies
Fahim, Asmaa M.
Tolan, Hala E. M.
El-Sayed, Wael A.
[J]. JOURNAL OF MOLECULAR STRUCTURE, 2022, 1251
[49] Design, synthesis, and in vitro and in vivo anti-angiogenesis study of a novel vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitor based on 1,2,3-triazole scaffold
Wang, De-pu
Liu, Kai-li
Li, Xin-yang
Lu, Guo-qing
Xue, Wen-han
Qian, Xin-hua
Mohamed, Kamara O.
Meng, Fan-hao
[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 211
[50] Mechanochemical Solvent-Free One-Pot Synthesis of Poly-Functionalized 5-(Arylselanyl)-1H-1,2,3-triazoles Through a Copper(I)-Catalyzed Click Reaction
Karmakar, Pintu
Karmakar, Indrajit
Mukherjee, Debojyoti
Bhowmick, Anindita
Brahmachari, Goutam
[J]. CHEMISTRY-A EUROPEAN JOURNAL, 2023, 29 (63)

← 1 2 3 4 5 →