Vaccine effectiveness against influenza hospitalisation in adults during the 2022/2023 mixed season of influenza A(H1N1)pdm09, A(H3N2) and B circulation, Europe: VEBIS SARI VE hospital network

被引:0
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作者
Rose, Angela M. C. [1 ]
Pozo, Francisco [2 ,3 ]
Martinez-Baz, Ivan [3 ,4 ]
Mazagatos, Clara [3 ,5 ]
Bossuyt, Nathalie [6 ]
Cauchi, John Paul [7 ]
Petrovic, Goranka [8 ]
Loghin, Isabela I. [9 ]
Vaikutyte, Roberta [10 ]
Buda, Silke [11 ]
Machado, Ausenda [12 ]
Duffy, Roisin [13 ]
Oroszi, Beatrix [14 ]
Howard, Jennifer [1 ]
Echeverria, Aitziber [3 ,4 ]
Andreu, Cristina [15 ]
Barbezange, Cyril [6 ]
Dziugyte, Ausra [7 ]
Nonkovic, Diana [16 ]
Popescu, Corneliu-Petru [17 ]
Majauskaite, Fausta [18 ]
Tolksdorf, Kristin [11 ]
Gomez, Veronica [12 ]
Domegan, Lisa [13 ]
Horvath, Judit Krisztina [14 ]
Castilla, Jesus [3 ,4 ]
Garcia, Miriam [19 ]
Demuyser, Thomas [20 ]
Borg, Maria-Louise [7 ]
Tabain, Irena [8 ]
Lazar, Mihaela [21 ]
Kubiliute, Ieva [18 ]
Duerrwald, Ralf [11 ]
Guiomar, Raquel [12 ]
O'Donnell, Joan [13 ]
Kristof, Katalin [14 ]
Nicolay, Nathalie [22 ]
Bacci, Sabrina [22 ]
Kissling, Esther [1 ]
机构
[1] Epiconcept, Paris, France
[2] Inst Hlth Carlos III, Natl Ctr Microbiol, Madrid, Spain
[3] Consortium Biomed Res Epidemiol & Publ Hlth CIBER, Madrid, Spain
[4] Inst Salud Publ Navarra IdiSNA, Pamplona, Spain
[5] Inst Hlth Carlos III, Natl Ctr Epidemiol, Madrid, Spain
[6] Sciensano, Brussels, Belgium
[7] Dept Hlth Regulat Hlth Promot & Dis Prevent, Msida, Malta
[8] Croatian Inst Publ Hlth, Zagreb, Croatia
[9] St Parascheva Clin Hosp Infect Dis, Iasi, Romania
[10] Lithuanian Univ Hlth Sci, Kaunas, Lithuania
[11] Robert Koch Inst, Berlin, Germany
[12] Natl Inst Hlth Dr Ricardo Jorge, Lisbon, Portugal
[13] Hlth Serv Execut Hlth Protect Surveillance Ctr, Dublin, Ireland
[14] Semmelweis Univ, Budapest, Hungary
[15] Serv Extremeno Salud, Subdirecc Epidemiol, Direcc Gen Salud Publ, Merida, Spain
[16] Teaching Publ Hlth Inst Split Dalmatia Cty, Split, Croatia
[17] Dr Victor Babes Clin Hosp Infect & Trop Dis, Bucharest, Romania
[18] Vilnius Univ, Inst Clin Med, Med Fac, Vilnius, Lithuania
[19] Dept San, Dept Sanidad, Gobierno Aragon, Zaragoza, Spain
[20] Dept Microbiol & Infect control, Dept Microbiol & Infect Control, Brussels, Belgium
[21] Cantacuzino Natl Mil Med Inst Res & Dev, Bucharest, Romania
[22] European Ctr Dis Prevent & Control, Stockholm, Sweden
关键词
hospital; influenza; SARI patients; test-negative design; vaccine effectiveness;
D O I
暂无
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We conducted a multicentre hospital-based test-negative case-control study to measure vaccine effectiveness (VE) against PCR-confirmed influenza in adult patients with severe acute respiratory infection (SARI) during the 2022/2023 influenza season in Europe. Among 5547 SARI patients >= 18 years, 2963 (53%) were vaccinated against influenza. Overall VE against influenza A(H1N1)pdm09 was 11% (95% CI: -23-36); 20% (95% CI: -4-39) against A(H3N2) and 56% (95% CI: 22-75) against B. During the 2022/2023 season, while VE against hospitalisation with influenza B was >55%, it was <= 20% for influenza A subtypes. While influenza vaccination should be a priority for future seasons, improved vaccines against influenza are needed.
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页数:9
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