Bronsted Acid-Catalyzed [5+1] and [4+1] Annulation of Cyclic Anhydrides with o-Alkynylanilines to Construct Fused-N-Heterocycles

被引：3

作者：

Das, Aranya ^{[1
]}

Ajarul, Sk ^{[2
]}

Debnath, Sudipto ^{[3
]}

Hota, Poulami ^{[1
]}

Maiti, Dilip K. ^{[1
]}

机构：

[1] Univ Calcutta, Dept Chem, Kolkata 700009, India

[2] Govt Gen Degree Coll Salboni, Paschim Medinipur 721516, India

[3] Govt India, Minist Ayush, Cent Ayurveda Res Inst, CCRAS, Kolkata 700091, India

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 88卷 / 21期

关键词：

C-H; FACILE SYNTHESIS; CYCLIZATION;

D O I：

10.1021/acs.joc.3c01525

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An unprecedented p-TsOH and MsOH-catalyzed construction of valuable isoindolo/pyrido/pyrrolo-quinolinediones and isoindolo-indolones is demonstrated through annulation reactions of cyclic anhydrides or o-formylbenzoates with o-alkynylanilines. The metal-free Bro.nsted acid-mediated new [5+1] and [4+1] fused-cyclization is an operationally simple, highly regioselective, atom economical, high yielding, sustainable, and catalytically efficient approach.

引用

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页码：15073 / 15084

页数：12

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