Critical disease related to SARS-CoV-2 infection in children from the Amazon region: an observational study

被引:0
作者
Farias, Emmerson Carlos Franco de [1 ]
Pavao Junior, Manoel Jaime Castro [1 ]
de Sales, Susan C. D. [1 ]
do Nascimento, Luciana M. P. P. [1 ]
de Mello, Mary [2 ]
Carvalho, Patricia [3 ]
Terreri, Maria Teresa [4 ]
Clemente, Gleice [4 ]
机构
[1] Fundacao Santa Casa Misericordia, Pediat Dept, Belem, Para, Brazil
[2] Hosp Pronto Socorro Municipal Mario Pinotti, Pediat Dept, Belem, Para, Brazil
[3] Fundacao Hosp Clin Gaspar Vianna, Pediat Dept, Belem, Para, Brazil
[4] Unifesp EPM, Pediat Rheumatol Dept, Sao Paulo, SP, Brazil
关键词
COVID-19; Epidemiology; Virology;
D O I
10.1136/bmjpo-2023-001865
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
This is a multicentre prospective cohort including critically ill children and adolescents, with confirmed critical disease related to SARS-CoV-2, admitted to three tertiary paediatric intensive care units in the Brazilian Amazon, between April 2020 and July 2022. 208 patients were included (median age was 3.5 years). The majority had malnutrition (62%) and comorbidities (60.6%). Mechanical ventilation support, cardiogenic shock and acute respiratory distress syndrome occurred in 47%, 30% and 34.1% of patients, respectively. There were 37 (18%) deaths. A poor outcome of severe COVID-19 and multisystem inflammatory syndrome in children was observed in children and adolescents from the Brazilian Amazon.
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