Early clinical and economic outcomes of expanded criteria living kidney donors in the United States

被引:0
作者
Nguyen, Nga T. Q. [1 ]
Courtney, Aisling E. E. [2 ]
Nguyen, Hoa Q. Q. [1 ,4 ]
Quinn, Michael [2 ]
Maxwell, Alexander P. P. [3 ,5 ]
O'Neill, Ciaran [5 ]
机构
[1] Univ Med & Pharm Ho Chi Minh City, Ben Nghe Ward, Fac Pharm, 41-43 Dinh Tien Hoang St, Dist 1, Ho Chi Minh City, Vietnam
[2] Belfast City Hosp, Reg Nephrol & Transplant Unit, Belfast, North Ireland
[3] Belfast City Hosp, Belfast, North Ireland
[4] Queens Univ Belfast, Sch Pharm, Belfast, North Ireland
[5] Queens Univ Belfast, Ctr Publ Hlth, Belfast, North Ireland
关键词
Economic outcomes; Expanded criteria kidneys; Living donor; Surgical complications; SURGICAL COMPLICATIONS; CLAVIEN-DINDO; DONATION; CLASSIFICATION; TRANSPLANTATION; HYPERTENSION; NEPHRECTOMY; INDEX;
D O I
10.1007/s40620-022-01541-4
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
BackgroundThe donation of what might be termed expanded criteria kidneys has become an increasingly common practice. This study aimed to assign expanded criteria and non-expanded criteria donation status and examine early clinical and economic outcomes among expanded criteria and non-expanded criteria living kidney donor (LKD) hospitalizations in the US. MethodsHealthcare cost and Utilization Project-National (Nationwide) Inpatient Sample (HCUP-NIS) data (Jan 2008-Dec 2019, N = 12,020) were used. Expanded criteria LKDs were identified as admitted patients aged & GE; 60 years, or 50-59 years with any comorbidity that historically precluded donation. The Clavien-Dindo system was applied to classify surgical complications as grade I-IV/V. ResultsThe number of LKD admissions decreased by 31% over the study period, although this trend fluctuated over time. Compared to non-expanded criteria LKD admissions, expanded criteria LKD admissions had comparable surgical complication rates in Grade I (aOR 1.0, 0.8-1.3), but significantly higher surgical complication rates in Grade II (aOR 1.5, 1.1-2.2) and Grade III (aOR 1.4, 1.0-2.0). The two groups had comparable hospital length of stay and cost in the adjusted models. Notably, Grade II complications were significantly higher in private, for-profit hospitals (15%) compared to government hospitals (2.9%). ConclusionsExpanded criteria LKDs had comparable early outcomes compared to non-expanded criteria LKDs, but the trends evident in LKDs over time and the variation in complication records warrant further research.
引用
收藏
页码:957 / 968
页数:12
相关论文
共 30 条
  • [1] Risk of ESKD in Older Live Kidney Donors with Hypertension
    Al Ammary, Fawaz
    Luo, Xun
    Muzaale, Abimereki D.
    Massie, Allan B.
    Crews, Deidra C.
    Waldram, Madeleine M.
    Qadi, Mohamud A.
    Garonzik-Wang, Jacqueline
    Henderson, Macey L.
    Brennan, Daniel C.
    Wiseman, Alexander C.
    Lindrooth, Richard C.
    Snyder, Jon J.
    Coresh, Josef
    Segev, Dorry L.
    [J]. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2019, 14 (07): : 1048 - 1055
  • [2] [Anonymous], 2022, Healthcare Cost and Utilization Project
  • [3] Living Kidney Donors Ages 70 and Older: Recipient and Donor Outcomes
    Berger, Jonathan C.
    Muzaale, Abimereki D.
    James, Nathan
    Hoque, Mohammed
    Wang, Jacqueline M. Garonzik
    Montgomery, Robert A.
    Massie, Allan B.
    Hall, Erin C.
    Segev, Dorry L.
    [J]. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2011, 6 (12): : 2887 - 2893
  • [4] Experiences with the standardized classification of surgical complications (Clavien-Dindo) in general surgery patients
    Bolliger, M.
    Kroehnert, J. -A.
    Molineus, F.
    Kandioler, D.
    Schindl, M.
    Riss, P.
    [J]. EUROPEAN SURGERY-ACTA CHIRURGICA AUSTRIACA, 2018, 50 (06): : 256 - 261
  • [5] Criteria for Living Donation from Marginal Donors: One, No One, and One Hundred Thousand
    Cantarelli, Chiara
    Cravedi, Paolo
    [J]. NEPHRON, 2019, 142 (03) : 227 - 232
  • [6] Assessment of Postdonation Outcomes in US Living Kidney Donors Using Publicly Available Data Sets
    Chen, Jieming
    Bhattacharya, Sanchita
    Sirota, Marina
    Laiudompitak, Sunisa
    Schaefer, Henry
    Thomson, Elizabeth
    Wiser, Jeff
    Sarwal, Minnie M.
    Butte, Atul J.
    [J]. JAMA NETWORK OPEN, 2019, 2 (04) : e191851
  • [7] The Clavien-Dindo Classification of Surgical Complications Five-Year Experience
    Clavien, Pierre A.
    Barkun, Jeffrey
    de Oliveira, Michelle L.
    Vauthey, Jean Nicolas
    Dindo, Daniel
    Schulick, Richard D.
    de Santibanes, Eduardo
    Pekolj, Juan
    Slankamenac, Ksenija
    Bassi, Claudio
    Graf, Rolf
    Vonlanthen, Rene
    Padbury, Robert
    Cameron, John L.
    Makuuchi, Masatoshi
    [J]. ANNALS OF SURGERY, 2009, 250 (02) : 187 - 196
  • [8] Cost of postoperative complications: How to avoid calculation errors
    de la Plaza Llamas, Roberto
    Ramia, Jose M.
    [J]. WORLD JOURNAL OF GASTROENTEROLOGY, 2020, 26 (21) : 2682 - 2690
  • [9] Department of Health and Human Services-Health Resources and Services Administration, 2022, NAT DAT ORG PROC TRA
  • [10] ADAPTING A CLINICAL COMORBIDITY INDEX FOR USE WITH ICD-9-CM ADMINISTRATIVE DATABASES
    DEYO, RA
    CHERKIN, DC
    CIOL, MA
    [J]. JOURNAL OF CLINICAL EPIDEMIOLOGY, 1992, 45 (06) : 613 - 619