SPILF update on bacterial arthritis in adults and children

被引:6
作者
Stahl, J. P. [1 ]
Canoui, E. [2 ]
Pavese, P. [3 ]
Bleibtreu, A. [4 ]
Dubee, V. [5 ]
Ferry, T. [6 ]
Gillet, Y. [7 ]
Lemaignen, A. [8 ]
Lorrot, M. [9 ]
Lourtet-Hascoet, J. [10 ]
Manaquin, R. [11 ]
Meyssonnier, V. [12 ,13 ]
Pham, T. -T [6 ,14 ]
Varon, E. [15 ]
Lesprit, P. [3 ]
Gauzit, R. [2 ]
机构
[1] Univ Grenoble Alpes, Malad Infect, F-38700 Grenoble, France
[2] Hop Cochin, Assistance Publ Hop Paris AP HP, Ctr Reference Infect Osteo Articulaires Complexes, Equipe Mobile Infectiol, Paris, France
[3] CHU Grenoble Alpes, Malad Infect, F-38043 Grenoble, France
[4] AP HP Sorbonne Univ, Hop Pitie Salpetriere, Malad Infect & Trop, Paris, France
[5] CHU Angers, Malad Infect & Trop, Angers, France
[6] Hosp Civils Lyon, Malad Infect & Trop, Ctr Reference Infect Osteo Articulaires Complexes, Hop Croix Rousse, F-69004 Lyon, France
[7] Univ Claude Bernard Lyon, Urgences & Reanimat Pediat, Hosp Civils Lyon, Lyon, France
[8] Univ Tours, Malad Infect, CHRU Tours, F-37044 Tours, France
[9] Hop Armand Trousseau AP HP Sorbonne Univ, Pediat Gen & Equipe Operat Infectiol, Ctr Reference Infect Osteo Articulaires Complexes, Paris, France
[10] Hop St Joseph, Microbiol Clin, F-75014 Paris, France
[11] CHU Reunion, Malad Infect & Trop, GHSR, CRAtb Reunion, F-97410 St Pierre, France
[12] GH Diaconesses Croix St Simon, Ctr Reference Infect Osteo Articulaires, F-75020 Paris, France
[13] Hop Univ Geneve, Dept Med, Serv Med Interne Gen, Geneva, Switzerland
[14] Hop Univ Geneve, Dept Med, Serv Malad Infect, Geneva, Switzerland
[15] Ctr Hosp Intercommunal Creteil, Ctr Natl Reference Pneumocoques, CRC CRB, F-94000 Creteil, France
来源
INFECTIOUS DISEASES NOW | 2023年 / 53卷 / 04期
关键词
Bacterial arthritis; Guidelines; Antibiotic treatment; Adults; Children; CLINICAL-PRACTICE GUIDELINES; INFECTIOUS-DISEASES SOCIETY; BLOOD-STREAM INFECTIONS; OF-THE-LITERATURE; SEPTIC ARTHRITIS; OSTEOARTICULAR INFECTIONS; STAPHYLOCOCCUS-AUREUS; JOINT INFECTIONS; PROPIONIBACTERIUM-ACNES; IN-VITRO;
D O I
10.1016/j.idnow.2023.104694
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
In 2020 the French Society of Rhumatology (SFR) published an update of the 1990 recommendations for management of bacterial arthritis in adults. While we (French ID Society, SPILF) totally endorse this update, we wished to provide further information about specific antibiotic treatments. The present update focuses on antibiotics with good distribution in bone and joint. It is important to monitor their dosage, which should be maximized according to PK/PD parameters. Dosages proposed in this update are high, with the optimized mode of administration for intravenous betalactams (continuous or intermittent infusion). We give tools for the best dosage adaptation to conditions such as obesity or renal insufficiency. In case of enterobacter infection, with an antibiogram result "susceptible for high dosage", we recommend the requesting of specialized advice from an ID physician. More often than not, it is possible to prescribe antibiotics via the oral route as soon as blood cultures are sterile and clinical have symptoms shown improvement. Duration of antibiotic treatment is 6 weeks for Staphylococcus aureus, and 4 weeks for the other bacteria (except for Neisseria: 7 days).
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页数:34
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