Long-Term Care and Follow-Up in Laryngeal Cancer Patients: A Multicenter Retrospective Analysis

被引:1
|
作者
Marijic, Blazen [1 ,2 ,3 ]
Tudor, Filip [2 ,3 ]
Janik, Stefan [4 ]
Grasl, Stefan [4 ]
Frommlet, Florian [5 ]
Marzic, Diana [3 ,6 ]
Hadzisejdic, Ita [3 ,7 ]
Vukelic, Jelena [3 ,6 ]
Braut, Tamara [2 ,3 ]
Velepic, Marko [2 ,3 ]
Erovic, Boban M. [1 ]
机构
[1] Evangel Hosp, Inst Head & Neck Dis, A-1180 Vienna, Austria
[2] Clin Hosp Ctr Rijeka, Dept Otorhinolaryngol Head & Neck Surg, Rijeka 51000, Croatia
[3] Univ Rijeka, Fac Med, Rijeka 51000, Croatia
[4] Med Univ Vienna, Dept Otorhinolaryngol Head & Neck Surg, A-1090 Vienna, Austria
[5] Med Univ Vienna, Ctr Med Stat Informat & Intelligent Syst, Sect Med Stat, A-1090 Vienna, Austria
[6] Clin Hosp Ctr Rijeka, Dept Audiol & Phoniatr, Rijeka 51000, Croatia
[7] Clin Hosp Ctr Rijeka, Clin Dept Pathol & Cytol, Rijeka 51000, Croatia
来源
JOURNAL OF PERSONALIZED MEDICINE | 2023年 / 13卷 / 06期
关键词
long-term care and follow-up; laryngeal carcinoma; secondary primary tumor; recurrence; survival; 2ND PRIMARY TUMORS; NECK-CANCER; HEAD; MALIGNANCIES; METASTASES; SURVEILLANCE; CARCINOMA; TRACT;
D O I
10.3390/jpm13060927
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Purpose: We conducted an outcome analysis on surgically treated laryngeal squamous cell carcinoma (LSCC) patients. Methods: A multicenter retrospective study with 352 patients was analyzed. A new nomogram that incorporates age, T- and N-classification, and treatment was created. Results: Recurrence was observed in 65 (18.5%) patients after a mean time of 16.5 months. After 60 months, 91 (25.9%) of patients developed secondary primary tumors (SPT), most commonly in the lungs (n = 29; 8.2%) followed by other head and neck cancers (n = 21; 6.0%). Notably, the mean time to occurrence of secondary head and neck cancers was twice that of lung cancer (101.1 vs. 47.5 months). Conclusion: Recurrent disease is less common in LSCC patients and appears much earlier than SPT. Because one in every four laryngeal cancer patients develops SPTs within 5-10 years, long-term care and follow-up, including imaging studies, are highly recommended. The nomogram was useful for estimating survival.
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页数:13
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