Hair follicle stem cells promote epidermal regeneration under expanded condition

被引:1
作者
Zhang, Yu [1 ]
Cui, Jiangbo [1 ]
Cang, Zhengqiang [1 ]
Pei, Jiaomiao [1 ]
Zhang, Xi [1 ]
Song, Baoqiang [1 ]
Fan, Xing [1 ]
Ma, Xianjie [1 ]
Li, Yang [1 ]
机构
[1] Fourth Mil Med Univ, Xijing Hosp, Dept Plast Surg, Xian, Shaanxi, Peoples R China
关键词
hair follicle stem cells; epidermal regeneration; skin soft tissue expansion; mechanical stretch; wound healing; SOFT-TISSUE DEFECTS; ENDOTHELIAL-CELLS; INFLAMMATORY MEMORY; CUTANEOUS WOUNDS; SKIN; REPAIR; EXPRESSION; CATENIN; GROWTH; NICHE;
D O I
10.3389/fphys.2024.1306011
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Skin soft tissue expansion is the process of obtaining excess skin mixed with skin development, wound healing, and mechanical stretching. Previous studies have reported that tissue expansion significantly induces epidermal proliferation throughout the skin. However, the mechanisms underlying epidermal regeneration during skin soft tissue expansion are yet to be clarified. Hair follicle stem cells (HFSCs) have been recognized as a promising approach for epidermal regeneration. This study examines HFSC-related epidermal regeneration mechanisms under expanded condition and proposes a potential method for its cellular and molecular regulation.
引用
收藏
页数:11
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