Local Methotrexate Plus Uterine Artery Embolization for High-Risk Interstitial Ectopic Pregnancy

被引:1
作者
Mikhitarian, Mark [1 ]
Goodnight, William [2 ]
Keefe, Nicole [1 ,3 ]
机构
[1] Univ N Carolina, Dept Radiol, Sch Med, Chapel Hill, NC USA
[2] Univ N Carolina, Dept Obstet & Gynecol, Sch Med, Chapel Hill, NC USA
[3] Univ N Carolina, Dept Radiol, Sch Med, 101 Manning Dr,CB 7510,2000 Old Clin Bldg, Chapel Hill, NC 27599 USA
关键词
interstitial ectopic pregnancy; uterine artery embolization; methotrexate; interventional radiology; MANAGEMENT;
D O I
10.1055/s-0043-1770712
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Interstitial ectopic pregnancy involves the interstitial portion of the fallopian tube and is among the most hazardous of all ectopic pregnancies, with the highest risk of uterine rupture and maternal mortality. Unlike tubal ectopic pregnancy, management of interstitial pregnancy is not well standardized. Systemic methotrexate (MTX) and surgical resection are the primary treatment options; however, failure rates and risk of bleeding remain high. Alternative minimally invasive techniques have been described-including uterine artery embolization (UAE) and local injection of MTX or potassium chloride-and may confer improved success rates. We report a case of a high-risk 28-year-old female with an interstitial ectopic pregnancy successfully treated with combined local injection of MTX plus UAE. We describe our technique and the unique medical management in the setting of a known bleeding disorder.
引用
收藏
页码:357 / 361
页数:5
相关论文
共 17 条
  • [1] INTERSTITIAL LINE - SONOGRAPHIC FINDING IN INTERSTITIAL (CORNUAL) ECTOPIC PREGNANCY
    ACKERMAN, TE
    LEVI, CS
    DASHEFSKY, SM
    HOLT, SC
    LINDSAY, DJ
    [J]. RADIOLOGY, 1993, 189 (01) : 83 - 87
  • [2] The medical management of ectopic pregnancy: A meta-analysis comparing "single dose" and "multidose" regimens
    Barnhart, KT
    Gosman, G
    Ashby, R
    Sammel, M
    [J]. OBSTETRICS AND GYNECOLOGY, 2003, 101 (04) : 778 - 784
  • [3] Serious primary post-partum hemorrhage, arterial embolization and future fertility: a retrospective study of 46 cases
    Chauleur, C.
    Fanget, C.
    Tourne, G.
    Levy, R.
    Larchez, C.
    Seffert, P.
    [J]. HUMAN REPRODUCTION, 2008, 23 (07) : 1553 - 1559
  • [4] Management of interstitial pregnancy using selective uterine artery embolization
    Deruelle, P
    Lucot, MP
    Lions, C
    Robert, Y
    [J]. OBSTETRICS AND GYNECOLOGY, 2005, 106 (05) : 1165 - 1167
  • [5] Uterine Artery Embolization and Methotrexate Infusion as Sole Management for Caesarean Scar and Cervical Ectopic Pregnancies: A Single-Center Experience and Literature Review
    Elmokadem, Ali H.
    Abdel-Wahab, Rihame M.
    El-Zayadi, Ahmed A.
    Elrakhawy, Mohamed M.
    [J]. CANADIAN ASSOCIATION OF RADIOLOGISTS JOURNAL-JOURNAL DE L ASSOCIATION CANADIENNE DES RADIOLOGISTES, 2019, 70 (03): : 307 - 316
  • [6] Embolization of a uterine arteriovenous malformation followed by a twin pregnancy
    Gopal, M
    Goldberg, J
    Klein, TA
    Fossum, GT
    [J]. OBSTETRICS AND GYNECOLOGY, 2003, 102 (04) : 696 - 698
  • [7] Uterine Artery Embolization Along With the Administration of Methotrexate for Cervical Ectopic Pregnancy: Technical and Clinical Outcomes
    Hirakawa, Masakazu
    Tajima, Tsuyoshi
    Yoshimitsu, Kengo
    Irie, Hiroyuki
    Ishigami, Kousei
    Yahata, Hideaki
    Wake, Norio
    Honda, Hiroshi
    [J]. AMERICAN JOURNAL OF ROENTGENOLOGY, 2009, 192 (06) : 1601 - 1607
  • [8] Kim Myung Joo, 2017, Obstet Gynecol Sci, V60, P571, DOI 10.5468/ogs.2017.60.6.571
  • [9] Conservative medical and surgical management of interstitial ectopic pregnancy
    Lau, S
    Tulandi, T
    [J]. FERTILITY AND STERILITY, 1999, 72 (02) : 207 - 215
  • [10] Medical therapy for ectopic pregnancy
    Lipscomb, Gary H.
    [J]. SEMINARS IN REPRODUCTIVE MEDICINE, 2007, 25 (02) : 93 - 98