共 50 条
- [1] The structure of human ATG9A and its interplay with the lipid bilayerAUTOPHAGY, 2020, 16 (12) : 2292 - 2293Guardia, Carlos M.论文数: 0 引用数: 0 h-index: 0机构: Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Sect Intracellular Prot Trafficking, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Sect Intracellular Prot Trafficking, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USAChristenson, Eric T.论文数: 0 引用数: 0 h-index: 0机构: Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Unit Struct & Chem Biol Membrane Prot, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Sect Intracellular Prot Trafficking, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USAZhou, Wenchang论文数: 0 引用数: 0 h-index: 0机构: NHLBI, Theoret Mol Biophys Lab, NIH, Bldg 10, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Sect Intracellular Prot Trafficking, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USATan, Xiao-Feng论文数: 0 引用数: 0 h-index: 0机构: NHLBI, Lab Membrane Prot & Struct Biol, Biochem & Biophys Ctr, NIH, Bldg 10, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Sect Intracellular Prot Trafficking, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USALian, Tengfei论文数: 0 引用数: 0 h-index: 0机构: NHLBI, Lab Membrane Prot & Struct Biol, Biochem & Biophys Ctr, NIH, Bldg 10, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Sect Intracellular Prot Trafficking, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USAFaraldo-Gomez, Jose D.论文数: 0 引用数: 0 h-index: 0机构: NHLBI, Theoret Mol Biophys Lab, NIH, Bldg 10, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Sect Intracellular Prot Trafficking, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USABonifacino, Juan S.论文数: 0 引用数: 0 h-index: 0机构: Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Sect Intracellular Prot Trafficking, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Sect Intracellular Prot Trafficking, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USAJiang, Jiansen论文数: 0 引用数: 0 h-index: 0机构: NHLBI, Lab Membrane Prot & Struct Biol, Biochem & Biophys Ctr, NIH, Bldg 10, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Sect Intracellular Prot Trafficking, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USABanerjee, Anirban论文数: 0 引用数: 0 h-index: 0机构: Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Unit Struct & Chem Biol Membrane Prot, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Sect Intracellular Prot Trafficking, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USA
- [2] Structure, lipid scrambling activity and role in autophagosome formation of ATG9ANature Structural & Molecular Biology, 2020, 27 : 1194 - 1201Shintaro Maeda论文数: 0 引用数: 0 h-index: 0机构: The Scripps Research Institute,Department of Integrative Structural and Computational BiologyHayashi Yamamoto论文数: 0 引用数: 0 h-index: 0机构: The Scripps Research Institute,Department of Integrative Structural and Computational BiologyLisa N. Kinch论文数: 0 引用数: 0 h-index: 0机构: The Scripps Research Institute,Department of Integrative Structural and Computational BiologyChristina M. Garza论文数: 0 引用数: 0 h-index: 0机构: The Scripps Research Institute,Department of Integrative Structural and Computational BiologySatoru Takahashi论文数: 0 引用数: 0 h-index: 0机构: The Scripps Research Institute,Department of Integrative Structural and Computational BiologyChinatsu Otomo论文数: 0 引用数: 0 h-index: 0机构: The Scripps Research Institute,Department of Integrative Structural and Computational BiologyNick V. Grishin论文数: 0 引用数: 0 h-index: 0机构: The Scripps Research Institute,Department of Integrative Structural and Computational BiologyStefano Forli论文数: 0 引用数: 0 h-index: 0机构: The Scripps Research Institute,Department of Integrative Structural and Computational BiologyNoboru Mizushima论文数: 0 引用数: 0 h-index: 0机构: The Scripps Research Institute,Department of Integrative Structural and Computational BiologyTakanori Otomo论文数: 0 引用数: 0 h-index: 0机构: The Scripps Research Institute,Department of Integrative Structural and Computational Biology
- [3] Structure, lipid scrambling activity and role in autophagosome formation of ATG9ANATURE STRUCTURAL & MOLECULAR BIOLOGY, 2020, 27 (12) : 1194 - U246Maeda, Shintaro论文数: 0 引用数: 0 h-index: 0机构: Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USA Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USAYamamoto, Hayashi论文数: 0 引用数: 0 h-index: 0机构: Univ Tokyo, Grad Sch Med, Dept Biochem & Mol Biol, Tokyo, Japan Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USAKinch, Lisa N.论文数: 0 引用数: 0 h-index: 0机构: Univ Texas Southwestern Med Ctr Dallas, Howard Hughes Med Inst, Dallas, TX USA Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USAGarza, Christina M.论文数: 0 引用数: 0 h-index: 0机构: Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USA Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USATakahashi, Satoru论文数: 0 引用数: 0 h-index: 0机构: Univ Tokyo, Grad Sch Med, Dept Biochem & Mol Biol, Tokyo, Japan Tokyo Med & Dent Univ, Grad Sch Med & Dent Sci, Dept Neurosurg, Tokyo, Japan Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USAOtomo, Chinatsu论文数: 0 引用数: 0 h-index: 0机构: Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USA Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USAGrishin, Nick V.论文数: 0 引用数: 0 h-index: 0机构: Univ Texas Southwestern Med Ctr Dallas, Howard Hughes Med Inst, Dallas, TX USA Univ Texas Southwestern Med Ctr Dallas, Dept Biophys, Dallas, TX 75390 USA Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USAForli, Stefano论文数: 0 引用数: 0 h-index: 0机构: Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USA Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USAMizushima, Noboru论文数: 0 引用数: 0 h-index: 0机构: Univ Tokyo, Grad Sch Med, Dept Biochem & Mol Biol, Tokyo, Japan Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USAOtomo, Takanori论文数: 0 引用数: 0 h-index: 0机构: Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USA Scripps Res Inst, Dept Integrat Struct & Computat Biol, La Jolla, CA 92037 USA
- [4] The autophagy protein ATG9A enables lipid mobilization from lipid dropletsNATURE COMMUNICATIONS, 2021, 12 (01)Mailler, Elodie论文数: 0 引用数: 0 h-index: 0机构: Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USAGuardia, Carlos M.论文数: 0 引用数: 0 h-index: 0机构: Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USABai, Xiaofei论文数: 0 引用数: 0 h-index: 0机构: NIDDK, Lab Biochem & Genet, NIH, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USAJarnik, Michal论文数: 0 引用数: 0 h-index: 0机构: Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USAWilliamson, Chad D.论文数: 0 引用数: 0 h-index: 0机构: Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USALi, Yan论文数: 0 引用数: 0 h-index: 0机构: NINDS, Prote Core Facil, NIH, Bldg 36,Rm 4D04, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USAMaio, Nunziata论文数: 0 引用数: 0 h-index: 0机构: Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Met Biol & Mol Med, Bethesda, MD USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USAGolden, Andy论文数: 0 引用数: 0 h-index: 0机构: NIDDK, Lab Biochem & Genet, NIH, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USABonifacino, Juan S.论文数: 0 引用数: 0 h-index: 0机构: Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USA Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Neurosci & Cellular & Struct Biol Div, NIH, Bethesda, MD 20892 USA
- [5] The autophagy protein ATG9A enables lipid mobilization from lipid dropletsNature Communications, 12Elodie Mailler论文数: 0 引用数: 0 h-index: 0机构: Neurosciences and Cellular and Structural Biology Division,Carlos M. Guardia论文数: 0 引用数: 0 h-index: 0机构: Neurosciences and Cellular and Structural Biology Division,Xiaofei Bai论文数: 0 引用数: 0 h-index: 0机构: Neurosciences and Cellular and Structural Biology Division,Michal Jarnik论文数: 0 引用数: 0 h-index: 0机构: Neurosciences and Cellular and Structural Biology Division,Chad D. Williamson论文数: 0 引用数: 0 h-index: 0机构: Neurosciences and Cellular and Structural Biology Division,Yan Li论文数: 0 引用数: 0 h-index: 0机构: Neurosciences and Cellular and Structural Biology Division,Nunziata Maio论文数: 0 引用数: 0 h-index: 0机构: Neurosciences and Cellular and Structural Biology Division,Andy Golden论文数: 0 引用数: 0 h-index: 0机构: Neurosciences and Cellular and Structural Biology Division,Juan S. Bonifacino论文数: 0 引用数: 0 h-index: 0机构: Neurosciences and Cellular and Structural Biology Division,
- [6] Imaging ATG9A, a Multi-Spanning Membrane ProteinJOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2023, (196):van Vliet, Alexander R.论文数: 0 引用数: 0 h-index: 0机构: Francis Crick Inst, Mol Cell Biol Autophagy, London, England MRC Lab Mol Biol, Cambridge, England Francis Crick Inst, Mol Cell Biol Autophagy, London, EnglandDe Tito, Stefano论文数: 0 引用数: 0 h-index: 0机构: Francis Crick Inst, Mol Cell Biol Autophagy, London, England Francis Crick Inst, Mol Cell Biol Autophagy, London, EnglandAlmacellas, Eugenia论文数: 0 引用数: 0 h-index: 0机构: Francis Crick Inst, Mol Cell Biol Autophagy, London, England Francis Crick Inst, Mol Cell Biol Autophagy, London, EnglandTooze, Sharon A.论文数: 0 引用数: 0 h-index: 0机构: Francis Crick Inst, Mol Cell Biol Autophagy, London, England Francis Crick Inst, Mol Cell Biol Autophagy, London, England
- [7] A noncanonical autophagy function of ATG9A for Golgi integrity and dynamicsAUTOPHAGY, 2023, 19 (05) : 1607 - 1608Meng, Yuanyuan论文数: 0 引用数: 0 h-index: 0机构: Nankai Univ, State Key Lab Med Chem Biol, Frontiers Sci Ctr Cell Responses, Tianjin Key Lab Prot Sci,Coll Life Sci, Tianjin, Peoples R China Nankai Univ, State Key Lab Med Chem Biol, Frontiers Sci Ctr Cell Responses, Tianjin Key Lab Prot Sci,Coll Life Sci, Tianjin, Peoples R ChinaLuo, Qian论文数: 0 引用数: 0 h-index: 0机构: Nankai Univ, State Key Lab Med Chem Biol, Frontiers Sci Ctr Cell Responses, Tianjin Key Lab Prot Sci,Coll Life Sci, Tianjin, Peoples R China Nankai Univ, State Key Lab Med Chem Biol, Frontiers Sci Ctr Cell Responses, Tianjin Key Lab Prot Sci,Coll Life Sci, Tianjin, Peoples R ChinaChen, Quan论文数: 0 引用数: 0 h-index: 0机构: Nankai Univ, State Key Lab Med Chem Biol, Frontiers Sci Ctr Cell Responses, Tianjin Key Lab Prot Sci,Coll Life Sci, Tianjin, Peoples R China Nankai Univ, State Key Lab Med Chem Biol, Frontiers Sci Ctr Cell Responses, Tianjin Key Lab Prot Sci,Coll Life Sci, Tianjin, Peoples R ChinaZhu, Yushan论文数: 0 引用数: 0 h-index: 0机构: Nankai Univ, State Key Lab Med Chem Biol, Frontiers Sci Ctr Cell Responses, Tianjin Key Lab Prot Sci,Coll Life Sci, Tianjin, Peoples R China Nankai Univ, State Key Lab Med Chem Biol, Frontiers Sci Ctr Cell Responses, Tianjin Key Lab Prot Sci,Coll Life Sci, Tianjin, Peoples R China
- [8] Structure of human ATG9A: how holey art thou?AUTOPHAGY, 2020, 16 (11) : 1929 - 1931Hawkins, Wayne D.论文数: 0 引用数: 0 h-index: 0机构: Univ Michigan, Life Sci Inst, Ann Arbor, MI 48109 USA Univ Michigan, Dept Mol Cellular & Dev Biol, Ann Arbor, MI 48109 USA Univ Michigan, Life Sci Inst, Ann Arbor, MI 48109 USAKlionsky, Daniel J.论文数: 0 引用数: 0 h-index: 0机构: Univ Michigan, Life Sci Inst, Ann Arbor, MI 48109 USA Univ Michigan, Dept Mol Cellular & Dev Biol, Ann Arbor, MI 48109 USA Univ Michigan, Life Sci Inst, Ann Arbor, MI 48109 USA
- [9] ATG9B is a tissue-specific homotrimeric lipid scramblase that can compensate for ATG9AAUTOPHAGY, 2024, 20 (03) : 557 - 576Chiduza, George N.论文数: 0 引用数: 0 h-index: 0机构: Francis Crick Inst, Mol Cell Biol Autophagy, London, England Francis Crick Inst, Mol Cell Biol Autophagy, London, EnglandGarza-Garcia, Acely论文数: 0 引用数: 0 h-index: 0机构: Francis Crick Inst, Mycobacterial Metab & Antibiot Res Lab, London, England Francis Crick Inst, Mol Cell Biol Autophagy, London, EnglandAlmacellas, Eugenia论文数: 0 引用数: 0 h-index: 0机构: Francis Crick Inst, Mol Cell Biol Autophagy, London, England Francis Crick Inst, Mol Cell Biol Autophagy, London, EnglandDe Tito, Stefano论文数: 0 引用数: 0 h-index: 0机构: Francis Crick Inst, Mol Cell Biol Autophagy, London, England Francis Crick Inst, Mol Cell Biol Autophagy, London, EnglandPye, Valerie E.论文数: 0 引用数: 0 h-index: 0机构: Francis Crick Inst, Chromatin Struct & Mobile DNA Lab, London, England Francis Crick Inst, Mol Cell Biol Autophagy, London, Englandvan Vliet, Alexander R.论文数: 0 引用数: 0 h-index: 0机构: Francis Crick Inst, Mol Cell Biol Autophagy, London, England Francis Crick Inst, Mol Cell Biol Autophagy, London, England论文数: 引用数: h-index:机构:Tooze, Sharon A.论文数: 0 引用数: 0 h-index: 0机构: Francis Crick Inst, Mol Cell Biol Autophagy, London, England Francis Crick Inst, Mol Cell Biol Autophagy, London NW1 1AT, England Francis Crick Inst, Mol Cell Biol Autophagy, London, England
- [10] ATG9A protects the plasma membrane from programmed and incidental permeabilizationNature Cell Biology, 2021, 23 : 846 - 858Aurore Claude-Taupin论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceJingyue Jia论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceZambarlal Bhujabal论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceMeriem Garfa-Traoré论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceSuresh Kumar论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceGustavo Peixoto Duarte da Silva论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceRuheena Javed论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceYuexi Gu论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceLee Allers论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceRyan Peters论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceFulong Wang论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceLuciana Jesus da Costa论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceSandeep Pallikkuth论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceKeith A. Lidke论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceMario Mauthe论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellencePauline Verlhac论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceYasuo Uchiyama论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceMichelle Salemi论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceBrett Phinney论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceSharon A. Tooze论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceMuriel C. Mari论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceTerje Johansen论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceFulvio Reggiori论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research ExcellenceVojo Deretic论文数: 0 引用数: 0 h-index: 0机构: University of New Mexico Health Sciences Center,Autophagy, Inflammation and Metabolic (AIM) Center of Biochemical Research Excellence