Chiral P,N,N-Ligands for Pd-Catalyzed Asymmetric Allylic Substitutions

被引：0
作者：
Qin Hao [1 ]
Hou Chuanjin [1 ,2 ]
Liang Dinghua [1 ]
He Xinwei [2 ]
Li Ling [1 ,3 ]
Hu Xiangping [3 ]
机构：
[1] Dalian Polytech Univ, Sch Light Ind & Chem Engn, Dalian 116034, Liaoning, Peoples R China
[2] Anhui Normal Univ, Key Lab Funct Mol Solids, Minist Educ, Wuhu 241000, Anhui, Peoples R China
[3] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Liaoning, Peoples R China
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 44卷 / 01期
关键词：
P; N; N-ligands; asymmetric allylic substitution; palladium; FORMAL 3+2 CYCLOADDITION; DECARBOXYLATIVE PROPARGYLIC ALKYLATION; ENANTIOSELECTIVE SYNTHESIS; IRIDIUM CATALYSTS; BETA-KETOESTERS; VICINAL TERTIARY; EFFICIENT ACCESS; HYDROGENATION; ESTERS; DEAROMATIZATION;
D O I：
10.6023/cjoc202306004
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Chiral P,N,N-ligands are a new type of ligands developed in recent years, which have been widely used in asymmetric catalytic reactions. In this study, chiral P,N,N-ligands were applied to palladium-catalyzed asymmetric allylic substitution reactions. The results showed that under mild conditions, various nucleophiles containing carbon, nitrogen and oxygen could react smoothly, achieving good yields (up to 97% yield) and enantioselectivities (up to 93% ee).
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收藏
页码：282 / 290
页数：9
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