Combination Therapy With Erlotinib and Ramucirumab in a Patient With Epidermal Growth Factor Receptor Mutation Positive Lung Adenocarcinoma and Interstitial Pneumonia: A Case Report

被引：0

作者：

Tanaka, Shunya ^{[1
]}

Tsuji, Taisuke ^{[1
]}

Jinno, Kazuki ^{[1
]}

Matsumoto, Shoki ^{[1
]}

机构：

[1] Japanese Red Cross Soc Kyoto Daiichi Hosp, Dept Resp Med, Kyoto, Japan

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 11期

关键词：

anti-ars antibody; nonspecific interstitial pneumonitis; anti-vegf inhibitor; egfr-tki; non-small cell lung adenocarcinoma; CANCER; DISEASE; EXACERBATION; EFFICACY; SAFETY;

D O I：

10.7759/cureus.49528

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Interstitial pneumonia often acts as a barrier to lung cancer treatment. We report the case of a 79-year-old man who was diagnosed with epidermal growth factor receptor (EGFR) mutation positive lung adenocarcinoma (T2aN0M0, stage IB, EGFR exon 19 deletion), and was positive for anti-aminoacyl-tRNA synthetase antibodies with interstitial pneumonia. Metastasis in the right seventh rib was detected three months after surgical resection and radiation therapy was initiated. As recurrence was observed at both ends of the radiation field five months later, combination chemotherapy with erlotinib and ramucirumab was initiated. Approximately one year has passed since the start initiation of treatment, and acute exacerbation of interstitial pneumonia has not been observed during the follow-up period observation. The tumor has remained stable, indicating stable disease.

引用

页数：7

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