Clinical and Structural Factors Affecting Ablation Outcomes in Atrial Fibrillation Patients-A Review

被引:3
作者
Brilliant, Justin [1 ]
Yadav, Ritu [1 ]
Akhtar, Tauseef [1 ]
Calkins, Hugh [1 ]
Trayanova, Natalia [1 ]
Spragg, David [1 ]
机构
[1] Johns Hopkins Univ Hosp, Div Cardiol, Baltimore, MD 21287 USA
关键词
Atrial fibrillation; catheter ablation; arrhythmia; pulmonary vein isolation; fibrosis; thrombogenesis; atrial myopathy; OBSTRUCTIVE SLEEP-APNEA; EPICARDIAL ADIPOSE-TISSUE; TYPE-2; DIABETES-MELLITUS; PULMONARY VEIN ISOLATION; CATHETER ABLATION; ANGIOTENSIN-II; BLOOD-PRESSURE; CARDIAC FIBROBLASTS; FOLLOW-UP; SUBSTRATE MODIFICATION;
D O I
10.2174/1573403X19666230331103153
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Catheter ablation is an effective and durable treatment option for patients with atrial fibrillation (AF). Ablation outcomes vary widely, with optimal results in patients with paroxysmal AF and diminishing results in patients with persistent or long-standing persistent AF. A number of clinical factors including obesity, hypertension, diabetes, obstructive sleep apnea, and alcohol use contribute to AF recurrence following ablation, likely through modulation of the atrial electro-anatomic substrate. In this article, we review the clinical risk factors and the electro-anatomic features that contribute to AF recurrence in patients undergoing ablation for AF.
引用
收藏
页码:83 / 96
页数:14
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