Association between electronic nicotine delivery systems use and risk of stroke: a meta-analysis of 1,024,401 participants

被引：8
作者：
Awad, Kamal [1 ,2 ]
Mohammed, Maged [1 ]
Martin, Seth S. [3 ]
Banach, Maciej [3 ,4 ,5 ]
机构：
[1] Zagazig Univ, Fac Med, Zagazig, El Sharkia, Egypt
[2] Hlth Insurance Org, Primary Hlth Care Ctr, Mashtoul Al Souq, El Sharkia, Egypt
[3] Johns Hopkins Ciccarone Ctr Prevent Cardiovasc Di, Baltimore, MD USA
[4] Med Univ Lodz MUL, Dept Prevent Cardiol & Lipidol, Lodz, Poland
[5] PMMHRI, Dept Cardiol & Adult Congenital Heart Dis, Lodz, Poland
来源：
ARCHIVES OF MEDICAL SCIENCE | 2023年 / 19卷 / 05期
基金：
中国国家自然科学基金;
关键词：
lifestyle changes; risk; prevention; smoking; stroke; OXIDATIVE STRESS; INFLAMMATION; OBESITY;
D O I：
10.5114/aoms/171473
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Introduction: To evaluate the relationship between electronic nicotine delivery systems (ENDS) use and the risk of stroke when compared to non-smokers. Methods: A comprehensive search was conducted until June 15, 2023. We included observational studies that assessed association of current or former usage of ENDS with risk of stroke compared with non-smokers, reported the risk estimate as odds ratio (OR) or hazard ratio (HR) and were adjusted for possible confounders. Results: 6 studies with 1,024,401 participants were included in our analysis. ENDS use was associated with a significant increased risk of stroke (OR = 1.52; 95% CI: 1.17-1.97) compared with non-users. A non-significant association was found between former ENDS use and risk of stroke (OR = 1.03; 95% CI: 0.87-1.21). Conclusions: The ENDS usage appears to be associated with a higher risk of stroke compared to non-use, whereas there was no association between former ENDS use and the risk of stroke.
引用
收藏
页码：1538 / 1544
页数：7
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