Recent advances in organelle-specific two-photon small-molecule fluorescent probes for bioanalysis in live tissues
被引:8
作者:
Lee, Hyo Won
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机构:
Ajou Univ, Dept Chem, Suwon 16499, South Korea
Ajou Univ, Res Inst Basic Sci, Suwon 16499, South KoreaAjou Univ, Dept Chem, Suwon 16499, South Korea
Lee, Hyo Won
[1
,2
]
Juvekar, Vinayak
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机构:
Ajou Univ, Dept Energy Syst Res, Suwon 16499, South KoreaAjou Univ, Dept Chem, Suwon 16499, South Korea
Juvekar, Vinayak
[3
]
Lee, Dong Joon
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机构:
Ajou Univ, Dept Energy Syst Res, Suwon 16499, South KoreaAjou Univ, Dept Chem, Suwon 16499, South Korea
Lee, Dong Joon
[3
]
Kim, Hwan Myung
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机构:
Ajou Univ, Dept Chem, Suwon 16499, South Korea
Ajou Univ, Dept Energy Syst Res, Suwon 16499, South KoreaAjou Univ, Dept Chem, Suwon 16499, South Korea
Kim, Hwan Myung
[1
,3
]
机构:
[1] Ajou Univ, Dept Chem, Suwon 16499, South Korea
[2] Ajou Univ, Res Inst Basic Sci, Suwon 16499, South Korea
[3] Ajou Univ, Dept Energy Syst Res, Suwon 16499, South Korea
Bioanalysis;
Live tissues;
Organelles;
Two-photon microscopy;
Two-photon probes;
ENDOPLASMIC-RETICULUM STRESS;
ISCHEMIA-REPERFUSION INJURY;
GAMMA-GLUTAMYL-TRANSPEPTIDASE;
LIPID DROPLETS;
GOLGI-APPARATUS;
ER STRESS;
OXIDATIVE STRESS;
HYDROGEN-SULFIDE;
LIVING CELLS;
VESICULAR TRANSPORT;
D O I:
10.1016/j.trac.2023.117128
中图分类号:
O65 [分析化学];
学科分类号:
070302 ;
081704 ;
摘要:
Biological events occur in specific cellular organelles to perform specialized roles in cells and collaborate with other organelles. Various methods have been used to study organelle dynamics, including two photon microscopy. This technique uses two near-infrared photons as an excitation source to generate high-resolution images over an extended period with minimal photo-toxicity and background noise. This review highlighted the design strategies, photo-physical properties, and bioimaging applications of recent two-photon probes for organelles in live samples. In this review, we focused on the development of two-photon probes specifically localized in the endoplasmic reticulum, Golgi, lipid droplets, lysosomes, plasma membrane, and mitochondria. The summary was limited to research from 2017 onwards.& COPY; 2023 Elsevier B.V. All rights reserved.
机构:
Sanford Burnham Med Res Inst, Degenerat Dis Program, La Jolla, CA 92037 USA
Univ Michigan, Dept Biol Chem, Med Ctr, Ann Arbor, MI 48109 USASanford Burnham Med Res Inst, Degenerat Dis Program, La Jolla, CA 92037 USA
Cao, Stewart Siyan
Kaufman, Randal J.
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机构:
Sanford Burnham Med Res Inst, Degenerat Dis Program, La Jolla, CA 92037 USASanford Burnham Med Res Inst, Degenerat Dis Program, La Jolla, CA 92037 USA
机构:
Sanford Burnham Med Res Inst, Degenerat Dis Program, La Jolla, CA 92037 USA
Univ Michigan, Dept Biol Chem, Med Ctr, Ann Arbor, MI 48109 USASanford Burnham Med Res Inst, Degenerat Dis Program, La Jolla, CA 92037 USA
Cao, Stewart Siyan
Kaufman, Randal J.
论文数: 0引用数: 0
h-index: 0
机构:
Sanford Burnham Med Res Inst, Degenerat Dis Program, La Jolla, CA 92037 USASanford Burnham Med Res Inst, Degenerat Dis Program, La Jolla, CA 92037 USA