Very Severe Aplastic Anemia in a 26-Year-Old Male: Implications for Prognosis and Treatment Options

被引：0
作者：
Alobaidi, Ahmed [1 ]
Albadry, Ahmed [2 ]
Murray, Anne [3 ]
机构：
[1] Methodist Hlth Syst, Internal Med, Dallas, TX 75203 USA
[2] Charles Univ Prague, Fac Med, Prague, Czech Republic
[3] Methodist Hlth Syst, Clin Res Inst, Dallas, TX USA
来源：
CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 09期
关键词：
pancytopenia; hematopoietic stem cell transplant; failure of the bone marrow; neutropenic fever; very severe aplastic anemia; BONE-MARROW-TRANSPLANTATION; OUTCOMES; CELLS;
D O I：
10.7759/cureus.45750
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Aplastic anemia (AA) is a hematopoietic stem cell (HSC) disorder characterized by the loss of HSCs, bone marrow failure, and peripheral pancytopenia. AA is classified as very severe (VSAA), severe (SAA), or nonsevere (NSAA) based on the severity criteria. This classification system has implications for the prognosis and treatment options offered to patients. The prognosis of AA has improved over the past several decades with the advancements in supportive care, HSC transplant (HCT), and immunosuppressive therapy (IST). In this report, we present the case of a 26 -year -old male diagnosed with VSAA after presenting with severe neutropenia and fever. The patient ultimately underwent HSC transplantation.
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