Post-Cardiac Arrest: Mechanisms, Management, and Future Perspectives

被引:32
作者
Lazzarin, Taline [1 ]
Tonon, Carolina Rodrigues [1 ]
Martins, Danilo [1 ]
Favero, Edson Luiz, Jr. [1 ]
Baumgratz, Thiago Dias [1 ]
Leal Pereira, Filipe Welson [1 ]
Pinheiro, Victor Rocha [1 ]
Ballarin, Raquel Simoes [1 ]
Rios Queiroz, Diego Aparecido [1 ]
Azevedo, Paula Schmidt [1 ]
Polegato, Bertha Furlan [1 ]
Okoshi, Marina Politi [1 ]
Zornoff, Leonardo [1 ]
Rupp de Paiva, Sergio Alberto [1 ]
Minicucci, Marcos Ferreira [1 ]
机构
[1] Univ Estadual Paulista UNESP, Botucatu Med Sch, Internal Med Dept, BR-18607741 Botucatu, SP, Brazil
关键词
cardiac arrest; targeted temperature management; rehabilitation; physiopathology; TARGETED TEMPERATURE MANAGEMENT; EUROPEAN-RESUSCITATION-COUNCIL; SUCCESSFUL CARDIOPULMONARY-RESUSCITATION; REVERSIBLE MYOCARDIAL DYSFUNCTION; CORONARY ANGIOGRAPHIC FINDINGS; CEREBRAL-BLOOD-FLOW; QUALITY-OF-LIFE; COMATOSE SURVIVORS; VENTRICULAR-FIBRILLATION; THERAPEUTIC HYPOTHERMIA;
D O I
10.3390/jcm12010259
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cardiac arrest is an important public health issue, with a survival rate of approximately 15 to 22%. A great proportion of these deaths occur after resuscitation due to post-cardiac arrest syndrome, which is characterized by the ischemia-reperfusion injury that affects the role body. Understanding physiopathology is mandatory to discover new treatment strategies and obtain better results. Besides improvements in cardiopulmonary resuscitation maneuvers, the great increase in survival rates observed in recent decades is due to new approaches to post-cardiac arrest care. In this review, we will discuss physiopathology, etiologies, and post-resuscitation care, emphasizing targeted temperature management, early coronary angiography, and rehabilitation.
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页数:25
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