Effects of Functional and Nutraceutical Foods in the Context of the Mediterranean Diet in Patients Diagnosed with Breast Cancer

被引:6
作者
Flore, Giovanna [1 ]
Deledda, Andrea [1 ]
Lombardo, Mauro [2 ]
Armani, Andrea [2 ,3 ]
Velluzzi, Fernanda
机构
[1] Univ Cagliari, Dept Med Sci & Publ Hlth, Obes Unit, I-09124 Cagliari, Italy
[2] San Raffaele Roma Open Univ, Dept Human Sci & Promot Qual Life, I-00166 Rome, Italy
[3] Ist Ricovero & Cura Carattere Sci IRCCS San Raffae, Lab Cardiovasc Endocrinol, I-00166 Rome, Italy
基金
英国科研创新办公室;
关键词
breast cancer; functional nutrition; Mediterranean diet; antioxidants; obesity; epigenetic; nutrigenomics; quality of life; therapy side effects; WEIGHT-LOSS; RISK-FACTORS; ALCOHOL-CONSUMPTION; FATTY-ACIDS; PPAR-GAMMA; THERAPEUTIC IMPLICATIONS; PLASMA CAROTENOIDS; FOLATE INTAKE; FERULIC ACID; APOPTOSIS;
D O I
10.3390/antiox12101845
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Several studies report that breast cancer survivors (BCS) tend to have a poor diet, as fruit, vegetable, and legume consumption is often reduced, resulting in a decreased intake of nutraceuticals. Moreover, weight gain has been commonly described among BCS during treatment, increasing recurrence rate and mortality. Improving lifestyle and nutrition after the diagnosis of BC may have important benefits on patients' general health and on specific clinical outcomes. The Mediterranean diet (MD), known for its multiple beneficial effects on health, can be considered a nutritional pool comprising several nutraceuticals: bioactive compounds and foods with anti-inflammatory and antioxidant effects. Recent scientific advances have led to the identification of nutraceuticals that could amplify the benefits of the MD and favorably influence gene expression in these patients. Nutraceuticals could have beneficial effects in the postdiagnostic phase of BC, including helping to mitigate the adverse effects of chemotherapy and radiotherapy. Moreover, the MD could be a valid and easy-to-follow option for managing excess weight. The aim of this narrative review is to evaluate the recent scientific literature on the possible beneficial effects of consuming functional and nutraceutical foods in the framework of MD in BCS.
引用
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页数:39
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