Improved detection of measurable residual disease in acute myeloid leukemia

被引：4

作者：

Zhang, Xuan ^{[1
]}

Grimes, H. Leighton ^{[1
]}

机构：

[1] Cincinnati Childrens Hosp Med Ctr, Div Immunobiol, Cincinnati, OH 45229 USA

来源：

SCIENCE ADVANCES | 2023年 / 9卷 / 38期

关键词：

D O I：

10.1126/sciadv.adk2533

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A novel multiplex single-cell genomic and immunophenotypic strategy leverages the sensitivity of MRD detection and distinguishes leukemic and preleukemic subpopulations.

引用

页数：3

共 3 条

[1] 2021 Update on MRD in acute myeloid leukemia: a consensus document from the European LeukemiaNet MRD Working Party [J].

Heuser, Michael ;

Freeman, Sylvie D. ;

Ossenkoppele, Gert J. ;

Buccisano, Francesco ;

Hourigan, Christopher S. ;

Ngai, Lok Lam ;

Tettero, Jesse M. ;

Bachas, Costa ;

Baer, Constance ;

Bene, Marie-Christine ;

Bucklein, Veit ;

Czyz, Anna ;

Denys, Barbara ;

Dillon, Richard ;

Feuring-Buske, Michaela ;

Guzman, Monica L. ;

Haferlach, Torsten ;

Han, Lina ;

Herzig, Julia K. ;

Jorgensen, Jeffrey L. ;

Kern, Wolfgang ;

Konopleva, Marina Y. ;

Lacombe, Francis ;

Libura, Marta ;

Majchrzak, Agata ;

Maurillo, Luca ;

Ofran, Yishai ;

Philippe, Jan ;

Plesa, Adriana ;

Preudhomme, Claude ;

Ravandi, Farhad ;

Roumier, Christophe ;

Subklewe, Marion ;

Thol, Felicitas ;

van de Loosdrecht, Arjan A. ;

van der Reijden, Bert A. ;

Venditti, Adriano ;

Wierzbowska, Agnieszka ;

Valk, Peter J. M. ;

Wood, Brent L. ;

Walter, Roland B. ;

Thiede, Christian ;

Dohner, Konstanze ;

Roboz, Gail J. ;

Cloos, Jacqueline .

BLOOD, 2021, 138 (26) :2753-2767

[2]

Robinson T., 2023, Sci. Adv, V9, peadg0488

[3] Deep sequencing in CD34+ cells from peripheral blood enables sensitive detection of measurable residual disease in AML [J].

Stasik, Sebastian ;

Burkhard-Meier, Clara ;

Kramer, Michael ;

Middeke, Jan M. ;

Oelschlaegel, Uta ;

Sockel, Katja ;

Ehninger, Gerhard ;

Serve, Hubert ;

Mueller-Tidow, Carsten ;

Baldus, Claudia D. ;

Roellig, Christoph ;

Bornhaeuser, Martin ;

Platzbecker, Uwe ;

Thiede, Christian .

BLOOD ADVANCES, 2022, 6 (11) :3294-3303

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