Two novel sesquiterpenes and one new monoterpene from the aerial part of Artemisia tournefortiana

被引:1
作者
Wu, Xiao-Fei [1 ,2 ]
Turak, Ablajan [1 ]
Aisa, Haji Akber [1 ]
机构
[1] Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, State Key Lab Basis Xinjiang Indigenous Med Plants, Key Lab Plant Resources & Chem Arid Reg, Urumqi 830011, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
基金
中国国家自然科学基金;
关键词
Artemisia tournefortiana; monoterpenes; anti-inflammation; cytotoxicity; antibacterial activity; CONSTITUENTS; ACETYLENES;
D O I
10.1080/10286020.2023.2230898
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Two novel sesquiterpenes and one new monoterpene, together with eight reported compounds were isolated from dichloromethane-soluble extract of the aerial part of Artemisia tournefortiana Reichb. Their relative and absolute structures were elucidated based on the analysis of 1D and 2D NMR spectra, HRESIMS, and calculated electronic circular dichroism (ECD). Two sesquiterpenes (1 and 2) showed no inhibition effect in anti-inflammatory and cytotoxic activity tests. Three new terpenes (1-3) were tested for antibacterial activity, compounds 2 and 3 showed moderate antibacterial activities with minimum inhibitory concentrations (MICs) between 264 and 556 & mu;g/ml.
引用
收藏
页码:334 / 341
页数:8
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