The association between smoking, changes in smoking behavior, and acute pancreatitis: A population-based cohort study in Korea

被引：2

作者：

Lee, Jae Min ^{[1
]}

Han, Kyung Do ^{[2
]}

Lee, Sang Hyub ^{[3
,4
,6
,7
]}

Park, Jin Myung ^{[5
,8
]}

Park, Namyoung ^{[3
,4
]}

Jeon, Hankyu ^{[1
]}

Kim, Hyun Jin ^{[1
]}

Ryu, Ji Kon ^{[3
,4
]}

Kim, Yong-Tae ^{[3
,4
]}

机构：

[1] Gyeongsang Natl Univ, Coll Med, Dept Internal Med, Changwon Hosp, Chang Won, South Korea

[2] Soongsil Univ, Dept Stat & Actuarial Sci, Seoul, South Korea

[3] Seoul Natl Univ, Seoul Natl Univ Hosp, Coll Med, Dept Internal Med, Seoul, South Korea

[4] Kangwon Natl Univ, Kangwon Natl Univ Hosp, Dept Internal Med, Sch Med, Chunchon, South Korea

[5] Seoul Natl Univ, Seoul Natl Univ Hosp, Liver Res Inst, Coll Med, Seoul, South Korea

[6] Seoul Natl Univ, Seoul Natl Univ Hosp, Coll Med, Dept Internal Med, 101 Daehak Ro, Seoul 03080, South Korea

[7] Seoul Natl Univ, Seoul Natl Univ Hosp, Liver Res Inst, Coll Med, 101 Daehak Ro, Seoul 03080, South Korea

[8] Kangwon Natl Univ, Kangwon Natl Univ Hosp, Sch Med cine, Dept Internal Med cine, 156 Baengnyeong Ro, Chunchon 24289, South Korea

来源：

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | 2023年 / 38卷 / 03期

关键词：

acute pancreatitis; population-based cohort study; smoking; CIGARETTE-SMOKING; DRINKING; RISK;

D O I：

10.1111/jgh.16061

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background and AimsIn the Asian population, existing studies regarding the association between smoking and acute pancreatitis are few in number. The aim of this study was to investigate the incidence of acute pancreatitis according to smoking habits and smoking habit changes of the Korean population. MethodsWe used clinical data from individuals (aged 20 years or older) who received health examinations arranged by the Korean National Health Insurance Service in 2009 (n = 4 238 822) or in 2009 and 2011 (n = 2 617 306). The incidence of acute pancreatitis was analyzed according to smoking status or smoking habit change reported by individuals during their health examination. Newly diagnosed acute pancreatitis was identified using claims data from baseline to the date of diagnosis or until December 31, 2018. ResultsThe risk of acute pancreatitis was significantly higher in current smokers compared with never-smokers regardless of age or sex. The adjusted hazard ratio (HR) of acute pancreatitis in current smokers increased according to the amount of smoking (HR 1.28; 95% confidence interval [CI], 1.12-1.45 in <10 cigarettes/day, HR 1.4; CI, 1.3-1.52 in 10-19 cigarettes/day, HR 1.66; CI, 1.55-1.78 in >= 20 cigarettes/day). The adjusted HR of acute pancreatitis in continuous smokers was 1.66 (CI, 1.53-1.8) compared with never-smokers and was higher than smokers who quit smoking (HR 1.34; CI, 1.17-1.54). ConclusionsIn this Korean population-based cohort study, smoking increased the incidence of acute pancreatitis in a dose-dependent manner, and smoking cessation helped decrease the incidence of acute pancreatitis.

引用

页码：451 / 459

页数：9

共 19 条

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