Mitochondrial oxidative stress, mitochondrial ROS storms in long COVID pathogenesis

被引：11

作者：

Noonong, Kunwadee ^{[1
,2
]}

Chatatikun, Moragot ^{[1
,3
]}

Surinkaew, Sirirat ^{[1
,3
]}

Kotepui, Manas ^{[1
]}

Hossain, Rahni ^{[1
]}

Bunluepuech, Kingkan ^{[4
]}

Noothong, Chanittha ^{[1
]}

Tedasen, Aman ^{[1
,2
]}

Klangbud, Wiyada Kwanhian ^{[1
,2
]}

Imai, Motoki ^{[5
,6
]}

Kawakami, Fumitaka ^{[6
,7
,8
]}

Kubo, Makoto ^{[6
,9
,10
]}

Kitagawa, Yoshimasa ^{[11
]}

Ichikawa, Hiroshi ^{[12
]}

Kanekura, Takuro ^{[13
]}

Sukati, Suriyan ^{[1
]}

Somsak, Voravuth ^{[1
,2
]}

Udomwech, Lunla ^{[4
]}

Ichikawa, Takafumi ^{[6
,7
]}

Nissapatorn, Veeranoot ^{[1
,2
]}

Tangpong, Jitbanjong ^{[1
,2
]}

Indo, Hiroko P. ^{[14
,15
]}

Majima, Hideyuki J. ^{[1
,2
]}

机构：

[1] Walailak Univ, Sch Allied Hlth Sci, Nakhon Si Thammarat, Thailand

[2] Walailak Univ, Res Excellence Ctr Innovat & Hlth Prod RECIHP, Sch Allied Hlth Sci, Nakhon Si Thammarat, Thailand

[3] Walailak Univ, Ctr Excellence Res Melioidosis & Microorganisms, Nakhon Si Thammarat, Thailand

[4] Walailak Univ, Sch Med, Nakhon Si Thammarat, Thailand

[5] Kitasato Univ, Sch Allied Hlth Sci, Dept Mol Diagnost, Sagamihara, Japan

[6] Kitasato Univ, Sch Allied Hlth Sci, Regenerat Med & Cell Design Res Facil, Sagamihara, Japan

[7] Kitasato Univ, Grad Sch Med Sci, Dept Regulat Biochem, Sagamihara, Japan

[8] Kitasato Univ, Sch Allied Hlth Sci, Dept Hlth Adm, Sagamihara, Japan

[9] Kitasato Univ, Sch Allied Hlth Sci, Div Microbiol, Sagamihara, Japan

[10] Kitasato Univ, Grad Sch Med Sci, Dept Environm Microbiol, Sagamihara, Japan

[11] Hokkaido Univ, Grad Sch Dent Med, Div Oral Pathobiol Sci, Oral Diag & Med, Sapporo, Japan

[12] Doshisha Univ, Grad Sch Life & Med Sci, Kyoto, Japan

[13] Kagoshima Univ, Grad Sch Med & Dent Sci, Dept Dermatol, Kagoshima, Japan

[14] Kagoshima Univ, Dept Oncol, Dept Radiol, Grad Sch Med & Dent Sci, Kagoshima, Japan

[15] Kagoshima Univ, Amanogawa Galaxy Astron Res Ctr, Grad Sch Engn, Kagoshima, Japan

来源：

FRONTIERS IN IMMUNOLOGY | 2023年 / 14卷

关键词：

COVID-19; oxidative stress; mitochondrial ROS storms; long Covid; mitochondria; DIABETES-MELLITUS; INJURY;

D O I：

10.3389/fimmu.2023.1275001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Significance: This review discusses the coronavirus disease 2019 (COVID-19) pathophysiology in the context of diabetes and intracellular reactions by COVID-19, including mitochondrial oxidative stress storms, mitochondrial ROS storms, and long COVID. Recent advances: The long COVID is suffered in similar to 10% of the COVID-19 patients. Even the virus does not exist, the patients suffer the long COVID for even over a year, This disease could be a mitochondria dysregulation disease. Critical issues: Patients who recover from COVID-19 can develop new or persistent symptoms of multi-organ complications lasting weeks or months, called long COVID. The underlying mechanisms involved in the long COVID is still unclear. Once the symptoms of long COVID persist, they cause significant damage, leading to numerous, persistent symptoms. Future directions: A comprehensive map of the stages and pathogenetic mechanisms related to long COVID and effective drugs to treat and prevent it are required, which will aid the development of future long COVID treatments and symptom relief.

引用

页数：10

共 50 条

[21] Insights into the Pathogenesis of Neurodegenerative Diseases: Focus on Mitochondrial Dysfunction and Oxidative Stress
Jurcau, Anamaria
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (21)
[22] COVID-19 Complications: Oxidative Stress, Inflammation, and Mitochondrial and Endothelial Dysfunction
Georgieva, Ekaterina
Ananiev, Julian
Yovchev, Yovcho
Arabadzhiev, Georgi
Abrashev, Hristo
Abrasheva, Despina
Atanasov, Vasil
Kostandieva, Rositsa
Mitev, Mitko
Petkova-Parlapanska, Kamelia
Karamalakova, Yanka
Koleva-Korkelia, Iliana
Tsoneva, Vanya
Nikolova, Galina
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (19)
[23] Impaired cardiac mitochondrial oxidative phosphorylation and enhanced mitochondrial oxidative stress in feline hypertrophic cardiomyopathy
Christiansen, Liselotte B.
Dela, Flemming
Koch, Jorgen
Hansen, Christina N.
Leifsson, Pall S.
Yokota, Takashi
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2015, 308 (10): : H1237 - H1247
[24] Impact of mitochondrial ROS production in the pathogenesis of insulin resistance
Nishikawa, Takeshi
Kukidome, Daisuke
Sonoda, Kazuhiro
Fujisawa, Kazuo
Matsuhisa, Takako
Motoshima, Hiroyuki
Matsumura, Takeshi
Araki, Eiichi
DIABETES RESEARCH AND CLINICAL PRACTICE, 2007, 77 : S161 - S164
[25] Mitochondrial L-arginine Transport Capacity: Implications for Oxidative Stress and the Pathogenesis of Heart Failure
Venardos, Kylie M.
Williams, David
Yang, Zhiyong
Byrne, Melissa
Kaye, David M.
CIRCULATION, 2010, 122 (21)
[26] Mitochondrial Oxidative Stress Mediates Bradyarrhythmia in Leigh Syndrome Mitochondrial Disease Mice
Chen, Biyi
Daneshgar, Nastaran
Lee, Hsiang-Chun
Song, Long-Sheng
Dai, Dao-Fu
ANTIOXIDANTS, 2023, 12 (05)
[27] Telomerase Impinges on the Cellular Response to Oxidative Stress Through Mitochondrial ROS-Mediated Regulation of Autophagy
Green, Paula D.
Sharma, Nilesh K.
Santos, Janine Hertzog
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (06)
[28] Mitochondrial biogenesis and mitochondrial DNA maintenance of mammalian cells under oxidative stress
Lee, HC
Wei, YH
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2005, 37 (04) : 822 - 834
[29] Mitochondrial damage induced by conditions of oxidative stress
Kowaltowski, AJ
Vercesi, AE
FREE RADICAL BIOLOGY AND MEDICINE, 1999, 26 (3-4) : 463 - 471
[30] Oxidative stress caused by mitochondrial calcium overload
Peng, Tsung-I
Jou, Mei-Jie
MITOCHONDRIAL RESEARCH IN TRANSLATIONAL MEDICINE, 2010, 1201 : 183 - 188

← 1 2 3 4 5 →