Vaccination in sickle cell disease: Immunocompromised or immunocompetent?

被引：2

作者：

Han, Jin ^{[1
]}

Saraf, Santosh L. ^{[2
]}

Gordeuk, Victor R. ^{[2
]}

机构：

[1] Univ Illinois, Coll Pharm, Dept Pharm Practice, 833 South Wood St,Suite 164, Chicago, IL 60612 USA

[2] Univ Illinois, Dept Med, Div Hematol & Oncol, Chicago, IL USA

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2023年

基金：

美国国家卫生研究院;

关键词：

antibody titer; COVID-19; immune response; sickle cell anaemia; sickle cell disease; vaccines; ANTIBODY-RESPONSES; CONJUGATE VACCINE; CHILDREN; IGG;

D O I：

10.1111/bjh.18942

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Sickle cell disease (SCD) is an immunocompromised condition and patients with SCD may have a reduced immune response to certain vaccinations. The report by Nakahara et al. demonstrated that SCD patients exhibited elevated and more sustained IgG production following COVID-19 vaccination, when compared to healthy controls. This suggests that the immune response to vaccinations may vary among different types of vaccines in individuals with SCD.

引用

页数：3

共 12 条

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