Development and validation of a nomogram for urinary tract infection in geriatric patients with hip fracture: a retrospective study

被引:0
作者
Tang, W. -Y. [1 ]
Wang, W. [1 ]
Yang, J. -X. [2 ]
Duan, X. -P. [3 ]
Yao, W. [1 ]
Lv, Q. -M. [4 ]
Ding, W. -B. [1 ]
He, R. -J. [5 ]
机构
[1] China Med Univ, Dandong Cent Hosp, Dept Orthoped, Dandong, Peoples R China
[2] Kunming Med Univ, Affiliated Hosp 2, Dept Urol, Kunming, Yunnan, Peoples R China
[3] Univ Sains Malaysia, Sch Hlth Sci, Hlth Campus, Kubang Kerian, Kelantan, Malaysia
[4] China Med Univ, Dandong Cent Hosp, Dept Oncol, Dandong, Peoples R China
[5] Zigong First Peoples Hosp, Dept Gastroenterol, Zigong, Sichuan, Peoples R China
关键词
Hip fracture; urinary tract infection; Geriatric; Prediction model; Nomogram; RISK-FACTORS; COMPLICATIONS; DIAGNOSIS; CATHETERIZATION; PREVENTION; PREVALENCE;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
OBJECTIVE: This study aims to develop and validate a risk nomogram for urinary tract infections (UTIs) in geriatric patients with hip fractures.PATIENTS AND METHODS: A total of 900 geriatric patients who underwent hip fracture surgery at Dandong Central Hospital between June 2017 and June 2023 were systematically collected. The cohort was randomly divided into a training set (70%, n=632) and a validation set (30%, n=268) for model development and validation, respectively. Univariate and multivariate logistic regression analyses were conducted to identify the independent risk factors associated with UTIs. Based on the results of the multivariate analysis, a UTI nomogram prediction model was developed and evaluated in the training and validation sets using the C-index, ROC curve, calibration curve, and decision curve analysis to assess discrimination, calibration, and clinical utility, respectively.RESULTS: Out of the 900 participants, 24.6% were diagnosed with UTIs. The nomogram was developed based on 9 predictors that were found to be independently associated with UTI. The area under the curve (AUC) for predicting UTI in geriatric patients with hip fractures was 0.829 in the training set and 0.803 in the validation set. Following internal verification, the modified C-index remained at 0.829. Furthermore, the nomogram's calibration plot and decision curve analysis demonstrated good performance in both the training and validation sets.CONCLUSIONS: The established and validated nomogram provides a reliable and convenient tool for predicting UTI risk in geriatric patients with hip fractures. This model facilitates the early identification of high-risk patients and offers guidance for implementing targeted preventive interventions.
引用
收藏
页码:10884 / 10898
页数:15
相关论文
共 41 条
[1]   Sex differences in lower urinary tract biology and physiology [J].
Abelson, Benjamin ;
Sun, Daniel ;
Que, Lauren ;
Nebel, Rebecca A. ;
Baker, Dylan ;
Popiel, Patrick ;
Amundsen, Cindy L. ;
Chai, Toby ;
Close, Clare ;
DiSanto, Michael ;
Fraser, Matthew O. ;
Kielb, Stephanie J. ;
Kuchel, George ;
Mueller, Elizabeth R. ;
Palmer, Mary H. ;
Parker-Autry, Candace ;
Wolfe, Alan J. ;
Damaser, Margot S. .
BIOLOGY OF SEX DIFFERENCES, 2018, 9
[2]   Perioperative urinary retention, short-term functional outcome and mortality rates of elderly hip fracture patients [J].
Adunsky, Abraham ;
Nenaydenko, Olga ;
Koren-Morag, Nira ;
Puritz, Lena ;
Fleissig, Yudit ;
Arad, Marina .
GERIATRICS & GERONTOLOGY INTERNATIONAL, 2015, 15 (01) :65-71
[3]   Changes in urine composition after trauma facilitate bacterial growth [J].
Aubron, Cecile ;
Huet, Olivier ;
Ricome, Sylvie ;
Borderie, Didier ;
Pussard, Eric ;
Leblanc, Pierre-Etienne ;
Bouvet, Odile ;
Vicaut, Eric ;
Denamur, Erick ;
Duranteau, Jacques .
BMC INFECTIOUS DISEASES, 2012, 12
[4]   Hyperglycemic Hyperosmolar State: A Pragmatic Approach to Properly Manage Sodium Derangements [J].
Baldrighi, Marco ;
Sainaghi, Pier P. ;
Bellan, Mattia ;
Bartoli, Ettore ;
Castello, Luigi M. .
CURRENT DIABETES REVIEWS, 2018, 14 (06) :534-541
[5]   Prosthetic joint infections and legal disputes: a threat to the future of prosthetic orthopedics [J].
Basile, Giuseppe ;
Gallina, Mario ;
Passeri, Alberto ;
Gaudio, Rosa Maria ;
Castelnuovo, Nicolo ;
Ferrante, Pasquale ;
Calori, Giorgio Maria .
JOURNAL OF ORTHOPAEDICS AND TRAUMATOLOGY, 2021, 22 (01)
[6]   Urinary tract infection in patients with hip fracture: An underestimated event? [J].
Bliemel, Christopher ;
Buecking, Benjamin ;
Hack, Juliana ;
Aigner, Rene ;
Eschbach, Daphne-Asimenia ;
Ruchholtz, Steffen ;
Oberkircher, Ludwig .
GERIATRICS & GERONTOLOGY INTERNATIONAL, 2017, 17 (12) :2369-2375
[7]   RETRACTED: Use of albumin: an update (Retracted article. See vol. 125, pg. 417, 2020) [J].
Boldt, J. .
BRITISH JOURNAL OF ANAESTHESIA, 2010, 104 (03) :276-284
[8]   Diagnosis, Management, and Prevention of Catheter-Associated Urinary Tract Infections [J].
Chenoweth, Carol E. ;
Gould, Carolyn V. ;
Saint, Sanjay .
INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 2014, 28 (01) :105-+
[9]  
Crouser Nisha, 2019, J Clin Orthop Trauma, V10, P774, DOI 10.1016/j.jcot.2018.07.014
[10]   Urinary tract infection in women [J].
Czajkowski, Krzysztof ;
Bros-Konopielko, Magdalena ;
Teliga-Czajkowska, Justyna .
MENOPAUSE REVIEW-PRZEGLAD MENOPAUZALNY, 2021, 20 (01) :40-47