Dietary flavonoids and gut microbiota interaction: A focus on animal and human studies tomaximize their health benefits

被引：37

作者：

Yang, Li ^{[1
]}

Gao, Yongchao ^{[2
]}

Farag, Mohamed A. ^{[3
]}

Gong, Jupeng ^{[4
]}

Su, Qiaoling ^{[4
]}

Cao, Hui ^{[4
,5
]}

Zhang, Wei ^{[2
]}

Zhao, Yonghua ^{[1
]}

Wang, Hui ^{[4
]}

机构：

[1] Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, Taipa 999078, Macao, Peoples R China

[2] Cent South Univ, Xiangya Hosp, Dept Clin Pharmacol, Changsha 410008, Peoples R China

[3] Cairo Univ, Dept Pharmacognosy, Coll Pharm, Cairo, Egypt

[4] Guangdong Ocean Univ, Coll Food Sci & Technol, Guangdong Prov Key Lab Aquat Product Proc & Safet, Zhanjiang, Peoples R China

[5] Univ Vigo, Dept Analyt & Food Chem, Nutr & Bromatol Grp, Fac Sci, Orense, Spain

来源：

FOOD FRONTIERS | 2023年 / 4卷 / 04期

基金：

中国国家自然科学基金;

关键词：

clinical application; flavonoids; gut microbiota; mechanism; pharmacology; PANCREATIC BETA-CELLS; FORMATION IN-VIVO; POLYPHENOL METABOLITES; PHENOLIC METABOLITES; INTESTINAL MICROBIOTA; ANTIOXIDANT ACTIVITY; COLONIC MICROBIOTA; GLUCOSE-TOLERANCE; OXIDATIVE STRESS; INDUCED OBESITY;

D O I：

10.1002/fft2.309

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Flavonoids are phytochemicals that widely exist in plants, fruits, and vegetables and have a variety of activities. However, due to their complex structure, it is often rarely absorbed into the blood. Intestinal bacteria regarded as the third kind of human organ have attracted extensive attention in recent years. Complex structural flavonoids can be catabolized into low molecular weight phenolic acids under the action of intestinal bacteria and then absorbed into the blood, showing several protective effects on the body. In addition, the intake of flavonoids can also regulate the composition and function of intestinal flora. This paper comprehensively summarizes the interaction between flavonoids and intestinal flora, aswell as the impact on human health, in order to provide some insights on how to combine intestinal microorganisms to select and ingest dietary polyphenols for future applications in medicine.

引用

页码：1794 / 1809

页数：16

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