Phenylglycine amphiphile-metal ion chiral supramolecular nanozymes for enantioselective catalysis

l/d-Phenylglycine amphiphiles and metal ions with peroxidase-like activity self-assembled into chiral nanoribbons, which act as efficient chiral supramolecular nanozymes for catalyzing the 3,4-dihydroxy-l/d-phenylalanine (l/d-DOPA) oxidation reactions. The catalytic efficiency and enantioselectivity are dominated by the chirality transfer and the synergistic effect between the metal ions and chiral nanoribbons. l/d-Phenylglycine chiral amphiphiles self-assembled with metal ions resulting in the construction of chiral supramolecular nanozymes (M/P), which exhibited high enantioselectivity and catalytic efficiency in the l/d-DOPA oxidation reactions.