Role of Adjuvant Radiotherapy in Acinic Cell Carcinoma of the Salivary Glands: A Systematic Review

被引：2

作者：

Patil, R. ^{[1
]}

Uzzaman, L. ^{[2
]}

Kelly, C. ^{[1
]}

Kovarik, J.

Jackson, M. ^{[1
]}

Paterson, C. ^{[3
,4
]}

Munro, S. P. ^{[5
]}

Wilson, A. ^{[6
]}

Iqbal, M. S. ^{[7
,8
]}

机构：

[1] Newcastle Tyne Hosp NHS Fdn Trust, Northern Ctr Canc Care, Dept Clin Oncol, Newcastle Upon Tyne, England

[2] Newcastle Tyne Hosp NHS Fdn Trust, Freeman Hosp, Dept Otolaryngol Head & Neck Surg, Newcastle Upon Tyne, England

[3] Beatson West Scotland Canc Ctr, Dept Clin Oncol, Glasgow, Scotland

[4] Univ Glasgow, Glasgow, Scotland

[5] Newcastle Univ, Sch Med, Newcastle Upon Tyne, England

[6] Sunderland Royal Hosp, Dept Oral & Maxillofacial Surg, Sunderland SR4 7TP, England

[7] Newcastle Univ, Newcastle Upon Tyne, England

[8] Newcastle Tyne Hosp NHS Fdn Trust, Freeman Hosp, Northern Ctr Canc Care, Dept Clin Oncol, Newcastle Upon Tyne NE7 7DN, England

来源：

CLINICAL ONCOLOGY | 2023年 / 35卷 / 09期

关键词：

Acinic cell carcinoma; adjuvant radiotherapy; risk factors; salivary gland cancer; survival; NATIONAL CANCER DATABASE; PROGNOSTIC-FACTORS; DECREASED SURVIVAL; RADIATION;

D O I：

10.1016/j.clon.2023.06.011

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A systematic review was carried out to evaluate if adjuvant radiotherapy for acinic cell carcinomas (ACCs) of salivary glands improves survival. Twelve retrospective studies published between 2000 and 2020 that analysed the effect of radiotherapy on salivary gland neoplasms and ACCs of salivary glands and met the inclusion criteria were included in the review. The overall quality of the studies was moderate to low. There was no high-quality evidence for improved survival with radiotherapy for ACCs of the salivary gland. Some evidence suggests that there may be an advantage for patients with high-grade tumours, but these data should be interpreted with caution due to the small number of patients and low-quality evidence. Good quality of evidence is lacking. Recom-mendation for adjuvant radiotherapy for tumours with poor prognostic factors will require discussion and shared decision-making with the patients.& COPY; 2023 Published by Elsevier Ltd on behalf of The Royal College of Radiologists.

引用

页码：E489 / E497

页数：9

共 20 条

[1]

Al-Zaher Nabil, 2009, Hematol Oncol Stem Cell Ther, V2, P259

[2] Radiotherapy in Parotid Acinic Cell Carcinoma Does It Have an Impact on Survival? [J].