Endoscopic mucosal resection with double band ligation versus endoscopic submucosal dissection for small rectal neuroendocrine tumors

被引:2
作者
Huang, Jia-Lan [1 ]
Gan, Ri-Yun [1 ]
Chen, Ze-Han [1 ]
Gao, Ruo-Yu [2 ]
Li, De-Feng [3 ,4 ]
Wang, Li-Sheng [3 ,4 ]
Yao, Jun [3 ,4 ,5 ,6 ]
机构
[1] Jinan Univ, Clin Med Coll 2, Dept Gastroenterol, Shenzhen 518020, Guangdong Provi, Peoples R China
[2] Shenzhen Luohu Peoples Hosp, Dept Gastroenterol, Shenzhen 518020, Guangdong Provi, Peoples R China
[3] Jinan Univ, Shenzhen Peoples Hosp, Clin Med Coll 2, Dept Gastroenterol, Shenzhen 518020, Guangdong Provi, Peoples R China
[4] Southern Univ Sci & Technol, Affiliated Hosp 1, Shenzhen 518020, Guangdong Provi, Peoples R China
[5] Jinan Univ, Shenzhen Peoples Hosp, Clin Med Coll 2, Dept Gastroenterol, 1017 East Gate Rd, Shenzhen 518020, Guangdong Provi, Peoples R China
[6] Southern Univ Sci & Technol, Affiliated Hosp 1, 1017 East Gate Rd, Shenzhen 518020, Guangdong Provi, Peoples R China
来源
WORLD JOURNAL OF GASTROINTESTINAL SURGERY | 2023年 / 15卷 / 03期
关键词
Small rectal neuroendocrine tumor; Endoscopic submucosal dissection; Endoscopic mucosal resection; Ligation; complete resection rate; Complication; CONSENSUS GUIDELINES UPDATE; METAANALYSIS; MANAGEMENT;
D O I
10.4240/wjgs.v15.i3.440
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
BACKGROUND Endoscopic resection remains an effective method for the treatment of small rectal neuroendocrine tumors (NETs) (<= 10 mm). Moreover, endoscopic mucosal resection (EMR) with double band ligation (EMR-dB), a simplified modification of EMR with band ligation, is an alternative strategy to remove small rectal NETs. AIM To evaluate the feasibility and safety of EMR-dB for the treatment of small rectal NETs (<= 10 mm). METHODSA total of 50 patients with small rectal NETs, without regional lymph node enlargement or distant metastasis confirmed by endoscopic ultrasound, computerized tomography scan, or magnetic resonance imaging, were enrolled in the study from March 2021 to June 2022. These patients were randomly assigned into the EMR-dB (n = 25) group or endoscopic submucosal dissection (ESD) group (n = 25). The characteristics of the patients and tumors, procedure time, devices cost, complete resection rate, complications, and recurrence outcomes were analyzed. RESULTS There were 25 patients (13 males, 12 females; age range 28-68 years old) in the EMR-dB group, and the ESD group contained 25 patients (15 males, 10 females; age range 25-70 years old). Both groups had similar lesion sizes (EMR-dB 4.53 +/- 1.02 mm, ESD 5.140 +/- 1.74 mm; P = 0.141) and resected lesion sizes(1.32 +/- 0.52 cm vs 1.58 +/- 0.84 cm; P = 0.269). Furthermore, the histological complete resection and en bloc resection rates were achieved in all patients (100% for each). In addition, there was no significant difference in the complication rate between the two groups. However, the procedure time was significantly shorter and the devices cost was significantly lower in the EMR-dB group. Besides, there was no recurrence in both groups during the follow-up period. CONCLUSION The procedure time of EMR-dB was shorter compared with ESD, and both approaches showed a similar curative effect. Taken together, EMR-dB was a feasible and safe option for the treatment of small rectal NETs.
引用
收藏
页数:11
相关论文
共 28 条
  • [1] Review article: the investigation and management of rectal neuroendocrine tumours
    Basuroy, R.
    Haji, A.
    Ramage, J. K.
    Quaglia, A.
    Srirajaskanthan, R.
    [J]. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2016, 44 (04) : 332 - 345
  • [2] Comparison of Endoscopic Resection Therapies for Rectal Carcinoid Tumor Endoscopic Submucosal Dissection Versus Endoscopic Mucosal Resection Using Band Ligation
    Choi, Cheol W.
    Kang, Dae H.
    Kim, Hyung W.
    Park, Su B.
    Jo, Woo S.
    Song, Geun A.
    Cho, Mong
    [J]. JOURNAL OF CLINICAL GASTROENTEROLOGY, 2013, 47 (05) : 432 - 436
  • [3] Updating the management of patients with rectal neuroendocrine tumors
    de Mestier, Louis
    Brixi, Hedia
    Gincul, Rodica
    Ponchon, Thierry
    Cadiot, Guillaume
    [J]. ENDOSCOPY, 2013, 45 (12) : 1039 - 1046
  • [4] ENETS Consensus Guidelines Update for Gastroduodenal Neuroendocrine Neoplasms
    Delle Fave, G.
    O'Toole, D.
    Sundin, A.
    Taal, B.
    Ferolla, P.
    Ramage, J. K.
    Ferone, D.
    Ito, T.
    Weber, W.
    Zheng-Pei, Z.
    De Herder, W. W.
    Pascher, A.
    Ruszniewski, P.
    [J]. NEUROENDOCRINOLOGY, 2016, 103 (02) : 119 - 124
  • [5] Is en bloc resection essential for endoscopic resection of GI neoplasia?
    Gotoda, Takuji
    Kaltenbach, Tonya
    Soetikno, Roy
    [J]. GASTROINTESTINAL ENDOSCOPY, 2008, 67 (06) : 805 - 807
  • [6] Endoscopic Mucosal Resection With Double Band Ligation for Small Rectal Neuroendocrine Tumors
    He, Long
    Wen, Wu
    Ye, Liansong
    Liao, Ke
    Hu, Bing
    [J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 2021, 116 (09) : 1827 - 1828
  • [7] Endoscopic mucosal resection with circumferential incision for treatment of rectal carcinoid tumours
    Huang, Jin
    Lu, Zhong-Sheng
    Yang, Yun-sheng
    Yuan, Jing
    Wang, Xiang-dong
    Meng, Jiang-yun
    Du, Hong
    Wang, Hong-bin
    [J]. WORLD JOURNAL OF SURGICAL ONCOLOGY, 2014, 12
  • [8] Clinical outcomes of rectal neuroendocrine tumors ≤ 10mm following endoscopic resection
    Kim, Gwang-Un
    Kim, Kyung-Jo
    Hong, Seung-Mo
    Yu, Eun-Sil
    Yang, Dong-Hoon
    Jung, Kee Wook
    Ye, Byong Duk
    Byeon, Jeong-Sik
    Myung, Seung-Jae
    Yang, Suk-Kyun
    Kim, Jin-Ho
    [J]. ENDOSCOPY, 2013, 45 (12) : 1018 - 1023
  • [9] Koura AN, 1997, CANCER, V79, P1294, DOI 10.1002/(SICI)1097-0142(19970401)79:7<1294::AID-CNCR4>3.0.CO
  • [10] 2-H