Infertility Treatment and Hypertension in Pregnancy: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study

被引：2

作者：

Ishikuro, Mami ^{[1
,2
]}

Obara, Taku ^{[1
,2
,3
]}

Murakami, Keiko ^{[1
,2
]}

Ueno, Fumihiko ^{[1
,2
]}

Noda, Aoi ^{[1
,2
,3
]}

Onuma, Tomomi ^{[1
,2
]}

Matsuzaki, Fumiko ^{[1
,2
]}

Kikuya, Masahiro ^{[1
,4
]}

Watanabe, Zen ^{[2
,3
]}

Shiga, Naomi ^{[2
,3
]}

Tachibana, Masahito ^{[2
]}

Iwama, Noriyuki ^{[1
,2
,3
]}

Hamada, Hirotaka ^{[2
,3
]}

Saito, Masatoshi ^{[2
,3
]}

Sugawara, Junichi ^{[1
,2
,3
,5
]}

Metoki, Hirohito ^{[1
,6
]}

Yaegashi, Nobuo ^{[1
,2
,3
]}

Kuriyama, Shinichi ^{[1
,2
,7
]}

机构：

[1] Tohoku Univ, Tohoku Med Megabank Org, 2-1 Seiryo Machi,Aoba Ku, Sendai 9808573, Japan

[2] Tohoku Univ, Grad Sch Med, 2-1 Seiryo Machi,Aoba Ku, Sendai 9808575, Japan

[3] Tohoku Univ Hosp, 1-1 Seiryo Machi,Aoba Ku, Sendai 9808574, Japan

[4] Teikyo Univ, Sch Med, 2-11-1 Kaga,Itabashi Ku, Tokyo 1738605, Japan

[5] Suzuki Mem Hosp, 3-5-5 Satonomori, Iwanuma 9892481, Japan

[6] Tohoku Med & Pharmaceut Univ, Fac Med, 1-15-1 Fukumuro,Miyagino Ku, Sendai 9838536, Japan

[7] Tohoku Univ, Int Res Inst Disaster Sci, 2-1 Seiryo Machi,Aoba Ku, Sendai 9808573, Japan

来源：

REPRODUCTIVE MEDICINE | 2023年 / 4卷 / 02期

关键词：

assisted conception; assisted reproductive technology; treatment for infertility; hypertensive disorders of pregnancy; cohort study; ASSISTED REPRODUCTIVE TECHNOLOGY; DISORDERS; OUTCOMES; RISK; COMPLICATIONS; METAANALYSIS;

D O I：

10.3390/reprodmed4020010

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Infertility treatment is a possible factor in hypertensive disorders of pregnancy (HDP). Identifying the characteristics of pregnant women who have undergone infertility treatment and have a potential risk for HDP is valuable for its prevention and treatment. Using data from 12,456 pregnant Japanese women from the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study, the association between infertility treatment and HDP was analyzed. A multiple logistic regression model showed an association between infertility treatment and HDP (odds ratio, 1.34; 95% confidence interval, 1.05-1.72). In vitro fertilization/intracytoplasmic sperm injection were also associated with HDP. Moreover, these associations were observed even among women who were not overweight and did not smoke. The application of infertility treatment should be carefully considered, even among women with low modifiable risk factors.

引用

页码：89 / 99

页数：11

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