Visualizing inflammatory monocytes and macrophages in the human heart

被引：0
作者：
Lavine, Kory [1 ]
Liu, Yongjian [1 ]
机构：
[1] Washington Univ, St Louis, MO 63130 USA
来源：
NATURE CARDIOVASCULAR RESEARCH | 2023年 / 2卷 / 10期
关键词：
D O I：
10.1038/s44161-023-00345-4
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Inflammatory monocytes and macrophages in the heart express C-C chemokine receptor 2 (CCR2) on their cell surface and contribute to heart failure pathogenesis. This study established the feasibility of imaging CCR2+ cells by positron emission tomography in patients with myocardial infarction.
引用
收藏
页码：869 / 870
页数：2
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    Itoh, Akinobu
    Shankar, Thirupura S.
    Selzman, Craig H.
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    Gierada, David S.
    Byers, Derek E.
    Gropler, Robert J.
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    Atkinson, Jeffrey J.
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