(E)-1-(5-Methyl-1-(4-nitrophenyl)-1H-1,2,3-triazol-4-yl)ethan-1-one Oxime

被引：4
|
作者：
Abdel-Wahab, Bakr F. [1 ]
Farahat, Abdelbasset A. [2 ,3 ]
Kariuki, Benson M. [4 ]
El-Hiti, Gamal A. [5 ]
机构：
[1] Chem Ind Res Inst, Natl Res Ctr, Appl Organ Chem Dept, Giza 12622, Egypt
[2] Calif Northstate Univ, Pharmaceut Sci Program, Elk Grove, CA 95757 USA
[3] Mansoura Univ, Fac Pharm, Dept Pharmaceut Organ Chem, Mansoura 35516, Egypt
[4] Cardiff Univ, Sch Chem, Main Bldg,Pk Pl, Cardiff CF10 3AT, Wales
[5] King Saud Univ, Coll Appl Med Sci, Dept Optometry, Riyadh 11433, Saudi Arabia
来源：
MOLBANK | 2023年 / 2023卷 / 01期
关键词：
triazoles; oximes; hydroxylamine hydrochloride; X-ray diffraction; heterocycles; synthesis; DERIVATIVES; INHIBITORS; HYBRIDS; ANALOGS;
D O I：
10.3390/M1593
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reaction of 1-(5-methyl-1-(4-nitrophenyl)-1H-1,2,3-triazol-4-yl)ethan-1-one (1) with excess hydroxylamine hydrochloride (2 mole equivalents) in dry ethanol afforded (E)-1-(5-methyl-1-(4-nitrophenyl)-1H-1,2,3-triazol-4-yl)ethan-1-one oxime (2) in 86% yield. The structure of the new heterocycle 2 was confirmed using nuclear magnetic resonance spectroscopy, single crystal X-ray and elemental analysis.
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页数：7
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