Microfluidic-Based Non-Invasive Wearable Biosensors for Real-Time Monitoring of Sweat Biomarkers

被引：22

作者：

Pour, Seyedeh Rojin Shariati ^{[1
]}

Calabria, Donato ^{[2
,3
]}

Emamiamin, Afsaneh ^{[1
]}

Lazzarini, Elisa ^{[2
]}

Pace, Andrea ^{[2
]}

Guardigli, Massimo ^{[2
,3
,4
]}

Zangheri, Martina ^{[1
,5
,6
]}

Mirasoli, Mara ^{[1
,3
,4
]}

机构：

[1] Univ Bologna, Dept Chem Giacomo Ciamician, Alma Mater Studiorum, Tecnopolo Rimini, Via Dario Campana 71, I-47922 Rimini, Italy

[2] Univ Bologna, Dept Chem Giacomo Ciamician, Alma Mater Studiorum, Via Francesco Selmi 2, I-40126 Bologna, Italy

[3] Univ Bologna, Interdept Ctr Ind Aerosp Res CIRI Aerosp, Alma Mater Studiorum, Via Baldassarre Canaccini 12, I-47121 Forli, Italy

[4] Univ Bologna, Interdept Ctr Ind Res Renewable Resources Environm, Alma Mater Studiorum, Via St Alberto 163, I-48123 Ravenna, Italy

[5] Univ Bologna, Interdept Ctr Ind Agrofood Res CIRI AGRO, Alma Mater Studiorum, Via Quinto Bucci 336, I-47521 Cesena, Italy

[6] Univ Bologna, Interdept Ctr Ind Res Adv Mech Engn Applicat & Mat, Alma Mater Studiorum, Viale Risorgimento 2, I-40136 Bologna, Italy

来源：

BIOSENSORS-BASEL | 2024年 / 14卷 / 01期

关键词：

wearable biosensors; point-of-care; sweat; colorimetric assay; electrochemical assay; enzymatic assay; immunoassay; COLORIMETRIC SENSOR; TATTOO SENSOR; PH; PLATFORM; HEALTH; DEVICE; CHALLENGES; LACTATE; GLUCOSE; DESIGN;

D O I：

10.3390/bios14010029

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Wearable biosensors are attracting great interest thanks to their high potential for providing clinical-diagnostic information in real time, exploiting non-invasive sampling of biofluids. In this context, sweat has been demonstrated to contain physiologically relevant biomarkers, even if it has not been exhaustively exploited till now. This biofluid has started to gain attention thanks to the applications offered by wearable biosensors, as it is easily collectable and can be used for continuous monitoring of some parameters. Several studies have reported electrochemical and optical biosensing strategies integrated with flexible, biocompatible, and innovative materials as platforms for biospecific recognition reactions. Furthermore, sampling systems as well as the transport of fluids by microfluidics have been implemented into portable and compact biosensors to improve the wearability of the overall analytical device. In this review, we report and discuss recent pioneering works about the development of sweat sensing technologies, focusing on opportunities and open issues that can be decisive for their applications in routine-personalized healthcare practices.

引用

页数：20

共 94 条

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