Hypovitaminosis D Implicated in the Development of Stress, Metabolic Syndrome and Hepatic Steatosis among Health Science Undergraduates attending a Tertiary Care Institute in Tamil Nadu, India

被引:0
作者
Aishwarya, S. K. [1 ]
Gayathri, B. [1 ]
Prabu, M. [1 ]
Renuka, P. [1 ]
Vinodhini, V. M. [1 ,2 ]
机构
[1] SRMIST, SRM Med Coll Hosp & Res Ctr, Dept Biochem, Chennai, Tamil Nadu, India
[2] SRMIST, SRM Med Coll Hosp & Res Ctr, Dept Biochem, Chennai 603203, Tamilnadu, India
关键词
Body mass index; Fatty liver; Stress score; Vitamin D; FATTY LIVER-DISEASE; SERUM 25-HYDROXYVITAMIN D; VITAMIN-D DEFICIENCY; ASSOCIATION; PREVALENCE; ADULTS; GENDER;
D O I
10.7860/JCDR/2023/60452.17809
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Introduction: Vitamin D deficiency is prevalent worldwide and its association with stress has become an emerging problem. A collection of linked physiological, biochemical, clinical, and metabolic risk factors is known as the Metabolic Syndrome (MS). High stress level is found associated with vitamin D deficiency and features of metabolic syndrome symptoms.Aim: To estimate the prevalence of vitamin D deficiency, perceived stress, metabolic syndrome and hepatic steatosis among health science Undergraduate (UG) students and also to evaluate the association of vitamin D with percieved stress score, calcium, phosphorus, components of metabolic syndrome and indicators of liver steatosis.Materials and Methods: This cross-sectional study was conducted in SRM Medical College, Hospital and Research Centre, Chennai, India, from February 2022 to August 2022. A total of 80 health science UG students in the age group of 19-25 years were included. The parameters included Fasting plasma glucose, Triglycerides (TGL), High Density Lipoprotein Cholesterol (HDLC), Gamma-glutamyl Transferase (GGT), phosphorus, calcium, and a Perceived Stress Scale (PSS) score scale. Data were statistically analysed using Pearson's correlation test and Receiver Operating Characteristic (ROC) curve was used to assess the relationship of vitamin D with stress, metabolic syndrome and liver steatosis.Results: In the present study, majority 56 (70%) had vitamin D deficiency, 23 (28.75%) had insufficiency and 1 (1.25%) had sufficiency. An estimated 6 (7.5%) of students experienced low stress, 63 (78.75%) experienced moderate stress and 11 (13.75%) experienced high perceived stress. Indicators of metabolic syndrome occurred in 13 (16.25%) of the population. Nearly 6 (7.5%) of the participants displayed manifestation of fatty liver. A negative association was found between vitamin D with stress score, Body Mass Index (BMI), waist circumference, Blood Pressure (BP), phosphorus, fasting plasma glucose, TGL, HDLC, GGT, Fatty Liver Index (FLI) score.Conclusion: In the present study, vitamin D deficiency was most prevalent (70%), followed by metabolic syndrome, high stress and hepatic steatosis. Vitamin D showed a negative correlation with stress score, BMI, waist circumference, BP, phosphorous, fasting plasma glucose, TGL, HDLC, GGT and FLI score.
引用
收藏
页码:BC7 / BC12
页数:6
相关论文
共 55 条
[1]   Vitamin D status and body composition: A cross-sectional study among employees at a private university in Lebanon [J].
Al Hayek S. ;
Matar Bou Mosleh J. ;
Ghadieh R. ;
El Hayek Fares J. .
BMC Nutrition, 4 (1)
[2]   Prevalence of vitamin D deficiency and association with metabolic syndrome in a Qatari population [J].
Al-Dabhani, K. ;
Tsilidis, K. K. ;
Murphy, N. ;
Ward, H. A. ;
Elliott, P. ;
Riboli, E. ;
Gunter, M. ;
Tzoulaki, I. .
NUTRITION & DIABETES, 2017, 7 :e263-e263
[3]   Association of 25-hydroxyvitamin D with HDL-cholesterol and other cardiovascular risk biomarkers in subjects with non-cardiac chest pain [J].
Alkhatatbeh, Mohammad J. ;
Amara, Noor A. ;
Abdul-Razzak, Khalid K. .
LIPIDS IN HEALTH AND DISEASE, 2019, 18 (1)
[4]  
Aparna P, 2018, J Family Med Prim Care, V7, P324, DOI 10.4103/jfmpc.jfmpc_78_18
[5]   Frequency of depression, anxiety and stress among university students [J].
Asif, Saba ;
Muddassar, Azka ;
Shahzad, Talala Zainab ;
Raouf, Mobeen ;
Pervaiz, Tehmina .
PAKISTAN JOURNAL OF MEDICAL SCIENCES, 2020, 36 (05) :971-976
[6]  
Bentley-Lewis R, 2023, NAT REV ENDOCRINOL, V17, pBC07
[7]   The appraisal of chronic stress and the development of the metabolic syndrome: a systematic review of prospective cohort studies [J].
Bergmann, N. ;
Gyntelberg, F. ;
Faber, J. .
ENDOCRINE CONNECTIONS, 2014, 3 (02) :R55-R80
[8]   Lower vitamin D levels are associated with higher blood glucose levels in Asian Indian women with pre-diabetes: a population-based cross-sectional study in North India [J].
Bhatt, Surya Prakash ;
Misra, Anoop ;
Gulati, Seema ;
Singh, Naamrata ;
Pandey, Ravindra Mohan .
BMJ OPEN DIABETES RESEARCH & CARE, 2018, 6 (01)
[9]   The Impact of Vitamin D in Non-Alcoholic Fatty Liver Disease: A Cross-Sectional Study in Patients with Morbid Obesity [J].
Borges-Canha, Marta ;
Neves, Joao Sergio ;
Mendonca, Fernando ;
Silva, Maria Manuel ;
Costa, Claudia ;
Cabral, Pedro M. ;
Guerreiro, Vanessa ;
Lourenco, Rita ;
Meira, Patricia ;
Salazar, Daniela ;
Ferreira, Maria Joao ;
Pedro, Jorge ;
Leite, Ana Rita ;
von-Hafe, Madalena ;
Vale, Catarina ;
Viana, Sara ;
Sande, Ana ;
Belo, Sandra ;
Lau, Eva ;
Freitas, Paula ;
Carvalho, Davide .
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY, 2021, 14 :487-495
[10]   Performance of Fatty Liver Index in Identifying Non-Alcoholic Fatty Liver Disease in Population Studies. A Meta-Analysis [J].
Castellana, Marco ;
Donghia, Rossella ;
Guerra, Vito ;
Procino, Filippo ;
Lampignano, Luisa ;
Castellana, Fabio ;
Zupo, Roberta ;
Sardone, Rodolfo ;
De Pergola, Giovanni ;
Romanelli, Francesco ;
Trimboli, Pierpaolo ;
Giannelli, Gianluigi .
JOURNAL OF CLINICAL MEDICINE, 2021, 10 (09)