Zinc(II) and copper(II) complexes with N-substituted imines derived from 4-amino-1,2,4-triazole: Synthesis, crystal structure, and biological activity

被引:16
作者
Bazhina, Evgeniya S. [1 ]
Bovkunova, Anna A. [1 ]
Shmelev, Maxim A. [1 ]
Korlyukov, Alexander A. [2 ]
Pavlov, Alexander A. [2 ]
Hochvaldova, Lucie [3 ]
Kvitek, Libor [3 ]
Panacek, Ales [3 ]
Kopel, Pavel [4 ]
Eremenko, Igor L. [1 ]
Kiskin, Mikhail A. [1 ]
机构
[1] Russian Acad Sci, NS Kurnakov Inst Gen & Inorgan Chem, Leninsky Prosp 31, Moscow 119991, Russia
[2] Russian Acad Sci, AN Nesmeyanov Inst Organoelement Cpds, Vavilova St 28, Moscow 119991, Russia
[3] Palacky Univ, Fac Sci, Dept Phys Chem, 17 Listopadu 12, CZ-77146 Olomouc, Czech Republic
[4] Palacky Univ, Fac Sci, Dept Inorgan Chem, 17 Listopadu 12, CZ-77146 Olomouc, Czech Republic
基金
俄罗斯科学基金会;
关键词
Zinc(II) complexes; Copper(II) complexes; Schiff base ligands; 4-Amino-1,2,4-triazole derivatives; X-ray diffraction; Biological activity; SCHIFF-BASE LIGAND; COORDINATION POLYMERS; MAGNETIC-PROPERTIES; ZN(II) COMPLEXES; SINGLE-CRYSTAL; X-RAY; NI(II); CU(II); 1,2,4-TRIAZOLE; ISOMERISM;
D O I
10.1016/j.ica.2022.121359
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Reactions of copper(II) and zinc(II) acetates with polynitrogen Schiff bases, namely 4-(pyridin-2-yl)methyl-eneamino-1,2,4-triazole (L-1), 4-(pyridin-3-yl)methyleneamino-1,2,4-triazole (L-2) and 4-(pyridin-4-yl)methyl-eneamino-1,2,4-triazole (L-3), were studied. The reaction of Zn(OAc)(2)center dot 2H(2)O and L1 gave crystals of trinuclear complex [Zn-3(OAc)(6)(L-1)(2)] (1). A similar reaction of Zn(OAc)(2)center dot 2H(2)O and L-2 resulted in 1D coordination polymer [Zn(OAc)(2)(L-2)]n (2). The reactions of Cu(OAc)(2)center dot H2O with L-2 or L-3 gave crystals of 1D coordination polymer {[Cu-2(OAc)(4)(L2)]center dot 2MeCN}n (3) and binuclear complex [Cu-2(OAc)(2)(L-3)(2)]center dot 2MeCN (4), respectively. The structures of the coordination compounds thus obtained were determined by single-crystal X-ray diffraction analysis. Complexes 1-4 demonstrated better antibacterial and antifungal activities in comparison with free L-1, L-2, and L-3 ligands: the strongest antimicrobial activity was observed against E. coli for 2 and 3, and the highest antifungal activity was found for 1 and 2.
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页数:9
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