Management of Melasma: Laser and Other Therapies-Review Study

被引:3
作者
Jiryis, Badea [1 ,2 ]
Toledano, Ohad [3 ]
Avitan-Hersh, Emily [1 ,2 ]
Khamaysi, Ziad [1 ,2 ]
机构
[1] Rambam Hlth Care Campus, Dept Dermatol, IL-3109601 Hefa, Israel
[2] Technion Israel Inst Technol, Bruce Rappaport Fac Med, IL-3525433 Hefa, Israel
[3] Alma Lasers Ltd, IL-38900 Caesarea, Israel
关键词
melasma; laser; treatment; SWITCHED NDYAG LASER; ALUMINUM-GARNET LASER; INTENSE PULSED-LIGHT; SPLIT-FACE; TRANEXAMIC ACID; FACIAL MELASMA; DOUBLE-BLIND; FRACTIONAL PHOTOTHERMOLYSIS; FLUOCINOLONE ACETONIDE; HYDROQUINONE; 4-PERCENT;
D O I
10.3390/jcm13051468
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Melasma is a commonly occurring pigmented skin condition that can significantly affect one's appearance, described as symmetric hyperpigmentation that presents as irregular brown to gray-brown macules on various facial areas, such as the cheeks, forehead, nasal bridge, and upper lip, along with the mandible and upper arms. Due to its complex pathogenesis and recurrent nature, melasma management is challenging and the outcomes following treatment are not always deemed satisfactory. Solely treating hyperpigmentation may prove ineffective unless paired with regenerative techniques and photoprotection, since one of the main reasons for recurrence is sun exposure. Hence, the treatment protocol starts with addressing risk factors, implementing stringent UV protection, and then treatment using different strategies, like applying topical treatments, employing chemical peels, laser and light therapies, microneedling, and systemic therapy. This review aims to provide a summary of the effectiveness and safety of the frequently employed laser and light therapies for treating melasma, focusing on laser therapy as a treatment for melasma.
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页数:12
相关论文
共 97 条
  • [21] Intradermal injection of tranexamic acid versus platelet-rich plasma in the treatment of melasma: a split-face comparative study
    Elraouf, Israa Gomaa Abd
    Obaid, Zakaria Mahran
    Fouda, Ibrahim
    [J]. ARCHIVES OF DERMATOLOGICAL RESEARCH, 2023, 315 (06) : 1763 - 1770
  • [22] Efficacy and safety of tranexamic acid in the treatment of adult melasma: An updated meta-analysis of randomized controlled trials
    Feng, Xiaowei
    Su, Hong
    Xie, Jinwei
    [J]. JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2021, 46 (05) : 1263 - 1273
  • [23] Comparative study between topical tranexamic acid alone versus its combination with autologous platelet rich plasma for treatment of melasma
    Gamea, Mohamed Mahmoud
    Kamal, Doha Ali
    Donia, Ahmed Atef
    Hegab, Doaa Salah
    [J]. JOURNAL OF DERMATOLOGICAL TREATMENT, 2022, 33 (02) : 798 - 804
  • [24] Goh Chee-Leok, 2018, J Clin Aesthet Dermatol, V11, P14
  • [25] Long-term results in low-fluence 1064-nm Q-Switched Nd:YAG laser for melasma: Is it effective?
    Gokalp, Hilal
    Akkaya, Ayse Deniz
    Oram, Yasemin
    [J]. JOURNAL OF COSMETIC DERMATOLOGY, 2016, 15 (04) : 420 - 426
  • [26] Histologic and ultrastructural analysis of melasma after fractional resurfacing
    Goldberg, David J.
    Berlin, Alexander L.
    Phelps, Robert
    [J]. LASERS IN SURGERY AND MEDICINE, 2008, 40 (02) : 134 - 138
  • [27] Efficacy and Safety of Fluocinolone Acetonide, Hydroquinone, and Tretinoin Cream in Chinese Patients with Melasma: A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Parallel-Group Study
    Gong, Zijian
    Lai, Wei
    Zhao, Guang
    Wang, Xuemin
    Zheng, Min
    Li, Li
    Yang, Qingqi
    Dang, Yuping
    Liu, Lunfei
    Zou, Ying
    [J]. CLINICAL DRUG INVESTIGATION, 2015, 35 (06) : 385 - 395
  • [28] TOPICAL TRETINOIN (RETINOIC ACID) IMPROVES MELASMA - A VEHICLE-CONTROLLED, CLINICAL-TRIAL
    GRIFFITHS, CEM
    FINKEL, LJ
    DITRE, CM
    HAMILTON, TA
    ELLIS, CN
    VOORHEES, JJ
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 1993, 129 (04) : 415 - 421
  • [29] Grimes P E, 2019, Int J Womens Dermatol, V5, P30, DOI 10.1016/j.ijwd.2018.09.004
  • [30] Grimes PE, 2004, CUTIS, V74, P362