Beliefs about antiretroviral therapy and their association with adherence in young people living with perinatal HIV in England: a cross-sectional analysis

被引:0
作者
White, Iona [1 ]
Judd, Ali [1 ]
Castro, Hannah [1 ]
Chappell, Elizabeth [1 ]
机构
[1] UCL, MRC Clin Trials Unit, 90 High Holborn,2nd Floor, London WC1V 6LJ, England
来源
AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV | 2024年 / 36卷 / 09期
关键词
beliefs; adherence; antiretroviral therapy; HIV; young people; MEDICATION ADHERENCE; INFECTED CHILDREN; ACQUIRED HIV; NONADHERENCE; ADOLESCENTS; MEDICINES; ADULTS; CARE;
D O I
10.1080/09540121.2023.2300984
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
This cross-sectional analysis aimed to describe beliefs about antiretroviral therapy (ART) in young people living with perinatal HIV (PHIV) in England, and the association between these beliefs and adherence to ART. The Beliefs About Medicine Questionnaire (Highly Active Antiretroviral Therapy version), was used to measure participants' beliefs in the necessity of ("Necessity score") and concerns regarding ("Concerns score") ART. Participants were classified as having high/low total scores using midpoints of the score scales. Associations between beliefs and being Last Month Adherent (LMA; self-reported not missing more than 2 consecutive ART doses in the month prior to the interview) were analysed using logistic regression, adjusting for sociodemographic, clinical, and psychosocial variables. Of 247 PHIV (median age = 18.6 years), 158 (64%) were LMA. 224 (91%) had a high Necessity score and 54 (22%) a high Concerns score. There was no association between high Necessity score and LMA in multivariable analysis (adjusted odds ratio (aOR) = 1.34, 95% confidence interval (CI) = 0.34-5.28, p = 0.679); however, high Concerns score was independently associated with a reduced odds of being LMA (aOR = 0.19, CI = 0.07-0.47, p < 0.001). Interventions to address the concerns young people living with PHIV have about ART should be explored as a strategy to improve their adherence.
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页码:1246 / 1262
页数:17
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