An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L.

被引：78

作者：

Shahane, Kiran ^{[1
]}

Kshirsagar, Madhuri ^{[1
]}

Tambe, Srushti ^{[1
]}

Jain, Divya ^{[1
]}

Rout, Srutee ^{[2
]}

Ferreira, Maria Karolina Martins ^{[3
]}

Mali, Suraj ^{[4
]}

Amin, Purnima ^{[1
]}

Srivastav, Prem Prakash ^{[2
]}

Cruz, Jorddy ^{[3
]}

Lima, Rafael Rodrigues ^{[3
]}

机构：

[1] Inst Chem Technol, Dept Pharmaceut Sci & Technol, Mumbai 400019, India

[2] Indian Inst Technol, Dept Agr & Food Engn, Kharagpur 721302, India

[3] Fed Univ Para, Inst Biol Sci, Lab Funct & Struct Biol, BR-66075110 Belem, Brazil

[4] Birla Inst Technol, Dept Pharmaceut Sci & Technol, Mesra 835215, India

来源：

PHARMACEUTICALS | 2023年 / 16卷 / 04期

关键词：

Calendula officinalis; traditional medicine; chemical composition; biological activities; ESSENTIAL OILS; IN-VITRO; CAROTENOID COMPOSITION; TRITERPENOID SAPONINS; ANTIFUNGAL ACTIVITY; MEDICINAL-PLANT; OLEANOLIC ACID; EXTRACT GEL; ANTIOXIDANT; MARIGOLD;

D O I：

10.3390/ph16040611

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Calendula officinalis Linn. (CO) is a popular medicinal plant from the plant kingdom's Asteraceae family that has been used for millennia. This plant contains flavonoids, triterpenoids, glycosides, saponins, carotenoids, volatile oil, amino acids, steroids, sterols, and quinines. These chemical constituents confer multifaceted biological effects such as anti-inflammatory, anti-cancer, antihelminthic, antidiabetes, wound healing, hepatoprotective, and antioxidant activities. Additionally, it is employed in cases of certain burns and gastrointestinal, gynecological, ocular, and skin conditions. In this review, we have discussed recent research from the last five years on the therapeutic applications of CO and emphasized its myriad capabilities as a traditional medicine. We have also elucidated CO's molecular mechanisms and recent clinical studies. Overall, this review intends to summarize, fill in the gaps in the existing research, and provide a wealth of possibilities for researchers working to validate traditional claims and advance the safe and effective use of CO in treating various ailments.

引用

页数：21

共 150 条

[1]

Abasova R. L., 1995, Chemistry of Natural Compounds, V30, P641, DOI 10.1007/BF00629888

[2]

Afolayan A.J, 2008, THESIS U FORT HARE A

[3] Osteosaponins 1 and 2: two new saponin glycosides from Osteospermum vaillantii [J].

Ahmed, Bahar ;

Khan, Riaz A. ;

Al-Howiriny, Tawfeq A. ;

Al-Rehaily, Adnan J. .

NATURAL PRODUCT RESEARCH, 2010, 24 (13) :1258-1267

[4] Chemical composition and biological activities of essential oils from Calendula officinalis L. flowers and leaves [J].

Ak, Gunes ;

Zengin, Gokhan ;

Ceylan, Ramazan ;

Mahomoodally, Mohamad Fawzi ;

Jugreet, Sharmeen ;

Mollica, Adriano ;

Stefanucci, Azzurra .

FLAVOUR AND FRAGRANCE JOURNAL, 2021, 36 (05) :554-563

[5] A Comparative Bio-Evaluation and Chemical Profiles ofCalendula officinalisL. Extracts Prepared via Different Extraction Techniques [J].

Ak, Gunes ;

Zengin, Gokhan ;

Sinan, Kouadio Ibrahime ;

Mahomoodally, Mohamad Fawzi ;

Picot-Allain, Marie Carene Nancy ;

Cakir, Oguz ;

Bensari, Souheir ;

Yilmaz, Mustafa Abdullah ;

Gallo, Monica ;

Montesano, Domenico .

APPLIED SCIENCES-BASEL, 2020, 10 (17)

[6] Identification and evaluation of in-vitro antioxidant phenolic compounds from the Calendula tripterocarpa Rupr [J].

Al-Rifai, A. .

SOUTH AFRICAN JOURNAL OF BOTANY, 2018, 116 :238-244

[7] Phytochemical standardization and biological activities of certain desert plants growing in Saudi Arabia [J].

Al-Saleem, Muneera S. ;

Awaad, Amani S. ;

Alothman, Monerah R. ;

Alqasoumi, Saleh I. .

SAUDI PHARMACEUTICAL JOURNAL, 2018, 26 (02) :198-204

[8]

Ali EM, 2017, J ESSENT OIL BEAR PL, V20, P1030, DOI [10.1080/0972060x.2017.1362998, 10.1080/0972060X.2017.1362998]

[9]

Hernández-Rosas Nancy Aline, 2018, TIP, V21, pe20180150, DOI [10.22201/fesz.23958723e.2018.0.150, 10.22201/fesz.23958723e.2018.0.150]

[10] Methoxylated flavonols from Vellozia dasypus Seub ethyl acetate active myeloperoxidase extract: in vitro and in silico assays [J].

Almeida, Veronica M. ;

Dias, Euder R. ;

Souza, Bruno C. ;

Cruz, Jorddy N. ;

Santos, Cleydson B. R. ;

Leite, Franco H. A. ;

Queiroz, Raphael F. ;

Branco, Alexsandro .

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2022, 40 (16) :7574-7583

← 1 2 3 4 5 6 7 8 9 10 →