Beyond the Hot Comb: Updates in Epidemiology, Pathogenesis, and Treatment of Central Centrifugal Cicatricial Alopecia from 2011 to 2021

被引：11

作者：

George, Elisabeth A. ^{[1
]}

Matthews, Caneisaya ^{[2
]}

Roche, Fritzlaine C. ^{[3
,4
]}

Taylor, Susan C. ^{[4
,5
,6
]}

机构：

[1] Brown Univ, Warren Alpert Med Sch, Providence, RI 02903 USA

[2] Florida State Univ, Coll Med, Tallahassee, FL 32304 USA

[3] Childrens Mercy Hosp & Clin, Kansas City, MO 64108 USA

[4] Washington Univ, Div Dermatol, Dept Med, St Louis, MO 63110 USA

[5] Univ Penn, Dept Dermatol, Perelman Sch Med, Philadelphia, PA 19104 USA

[6] Perelman Ctr Adv Med, Dept Dermatol, 3400 Civ Ctr Blvd, Philadelphia, PA 19104 USA

来源：

AMERICAN JOURNAL OF CLINICAL DERMATOLOGY | 2023年 / 24卷 / 01期

关键词：

HAIR TRANSPLANTATION; DIAGNOSIS; CHALLENGES;

D O I：

10.1007/s40257-022-00740-w

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Central centrifugal cicatricial alopecia (CCCA) is a form of scarring alopecia that predominantly affects middle-aged women of African descent. Recent data suggest a multifactorial etiology of CCCA that is influenced by environmental and genetic factors. Emerging evidence regarding the genetic basis of the condition may elucidate new therapies. While topical and intralesional steroids and tetracycline antibiotics are the mainstay of treatment, refractory cases may be considered for hair transplantation. Emerging therapies using platelet-rich plasma, botanical formulas, and cosmetic procedures have shown promising results for the future management of CCA. As recent notable advances in CCCA have been achieved, this review provides an update on the epidemiology, pathophysiology, and management of CCCA.

引用

页码：81 / 88

页数：8

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