Effect of Gas Bubbles on the Recovery Efficiency of Paclitaxel from Biomass of Taxus chinensis in Ultrasonic Extraction

被引:3
作者
Jeon, Hyo-Jin [1 ]
Kim, Jin-Hyun [1 ]
机构
[1] Kongju Natl Univ, Ctr Future Sustainable Technol, Dept Chem Engn, Cheonan 31080, South Korea
基金
新加坡国家研究基金会;
关键词
paclitaxel; extraction; cavitation bubble; gas bubble; synergistic effect; MICROWAVE-ASSISTED EXTRACTION; FRACTIONAL PRECIPITATION; KINETICS; PURIFICATION; FLAVONOIDS; CULTURE; TAXOL;
D O I
10.1007/s12257-023-0023-6
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The synergistic effect of introducing both ultrasonic cavitation bubbles and gas bubbles to the extraction of paclitaxel from Taxus chinensis biomass was investigated. The addition of gas bubbles to ultrasonic extraction significantly improved the extraction efficiency, confirming that ultrasonic cavitation bubbles and gas bubbles have a synergistic effect. Furthermore, an ultrasonic power of 250 W and a gas flow rate of 1.750 L/min could recover up to 94% of the paclitaxel from the biomass. In addition, as the ultrasonic power and gas flow rate increased, the extraction rate constant, the effective diffusion coefficient, and the mass transfer coefficient also increased. The efficiency of paclitaxel extraction was improved by the efficient crushing of the biomass facilitated by the synergistic effect of the ultrasonic cavitation bubbles and the gas bubbles.
引用
收藏
页码:545 / 553
页数:9
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