Aim. To substantiate and develop a program of physical and health promotion activities for students with different health levels. Materials and methods. The study involved 64 female students, ages 19-21, from the main medical group. In the experimental group, health promotion activities included health-enhancing aerobic exercises. The following research methods were used: literature review, pedagogical testing, anthropometrical measurements, functional tests and related indicators, pedagogical experiment, and mathematical statistics. Results. Two programs of health-enhancing aerobic exercises were developed with respect to the health levels and motor abilities of students. Our nine-month program included two 90-minute classes per week. The main feature of the program was the integration of two programs into a single training module, "Health-enhancing aerobic exercises". The first program contributed to the improvement of morphological indicators in female students, including circumference measurements (waist by 8.2 %, shoulders by 9.2 %, hips by 6.3 %, buttocks by 5.3 %). After the first semester, 34.5 % of female students improved their physical fitness and entered a new functional group with more intense aerobic exercise. Conclusions. The study shows that our complex two-level system of health-enhancing aerobic exercises resulted in the development of various morphofunctional parameters. A significant increase was recorded for such parameters as flexibility (82 %), speed and strength (28 %), and dynamic strength (22 %). The proposed program allowed female students with different health levels to unite while differentiating their physical activities and individualizing the approach to each student.