Recent advances in the metal/organic hybrid nanomaterials for cancer theranostics

被引:22
作者
Ye, Zhaoyi [1 ]
Bao, Ying [1 ]
Chen, Zefeng [2 ]
Ye, Huiling [1 ]
Feng, Zhenzhen [1 ]
Li, Yushan [1 ]
Zeng, Yaoxun [1 ]
Pan, Zhenxing [1 ]
Ouyang, Defang [3 ]
Zhang, Kun [1 ]
Liu, Xujie [1 ,4 ]
He, Yan [1 ,4 ]
机构
[1] Guangdong Univ Technol, Sch Biomed & Pharmaceut Sci, Guangzhou 510006, Peoples R China
[2] Hong Kong Baptist Univ, Inst Integrated Bioinfomed & Translat Sci, Sch Chinese Med, Kowloon Tsai, Hong Kong 999077, Peoples R China
[3] Univ Macau, Inst Chinese Med Sci ICMS, State Key Lab Qual Res Chinese Med, Taipa 999078, Macau, Peoples R China
[4] Guangdong Univ Technol, Sch Biomed & Pharmaceut Sci, Guangzhou Higher Educ Mega Ctr, 100 Wai Huan West Rd, Guangzhou 510006, Peoples R China
基金
中国国家自然科学基金;
关键词
Metal/organic hybrid nanomaterials; Organic ligand; Cancer theranostics; METAL-ORGANIC FRAMEWORKS; NANOSCALE COORDINATION POLYMERS; IMMUNOGENIC CELL-DEATH; RESONANCE-IMAGING MRI; IN-VIVO; PHOTODYNAMIC THERAPY; TUMOR MICROENVIRONMENT; PHOTOTHERMAL THERAPY; PHOTOACOUSTIC TOMOGRAPHY; CONJUGATED POLYMER;
D O I
10.1016/j.ccr.2023.215654
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Cancer is an extremely significant disease that profoundly impacts human survival and quality of life. Researchers have been searching for effective therapies, among which metal/organic hybrid nanomaterials received widespread attention due to their tumor imaging and treatment capabilities. Metal/organic hybrid nanomaterials are easy to modify and possess magnetic and plasma resonance, catalytic function, and biological activity. Then, researchers have recently designed a series of highly efficient metal/organic hybrid nanomaterials with integrated theranostics, good biocompatibility, and relative safety for achieving excellent therapeutic outcomes in cancer combined with various treatment methods. This paper highlights the research progress of metal/organic hybrid nanomaterials in the single diagnosis and treatment of cancer and their integration into diagnosis and treatment. The development trends, key problems, future outlook, and challenges of metal/organic hybrid nanomaterials are summarized and discussed. It is expected that the metal nanoparticles discussed in this paper can provide insights into the early diagnosis and effective treatment of cancer.
引用
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页数:34
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