Remote Steric Control for Site-Selective Synthesis

被引：5

作者：

Asako, Sobi ^{[1
]}

Ilies, Laurean ^{[1
]}

机构：

[1] RIKEN Ctr Sustainable Resource Sci, 2-1 Hirosawa, Wako, Saitama 3510198, Japan

来源：

SYNLETT | 2023年

基金：

日本学术振兴会;

关键词：

steric control; site selectivity; remote control; C-H activation; transition-metal catalysis; C-H BORYLATION; IRIDIUM-CATALYZED BORYLATION; STEREOSELECTIVE FUNCTIONALIZATION; 1,2-DISUBSTITUTED BENZENES; BOND FUNCTIONALIZATION; ARENES; ACTIVATION; EVOLUTION; INSIGHTS; DIBORON;

D O I：

10.1055/a-2126-1835

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Control of site selectivity for organic synthesis in general, and for transition-metal-catalyzed C-H functionalization in particular, is an important and challenging task. Steric interactions have been widely used to control reaction selectivity, but these strategies are largely limited to proximity sites. Recently, control of site selectivity through remote steric interactions has emerged as an attractive strategy that can enable selective reactions at distal sites from a steric marker. This review will cover recent developments in this area, with a focus on borylation reactions and transition-metal-catalyzed C-H activation.

引用

页码：2110 / 2116

页数：7