The role of vaccines in the COVID-19 pandemic: what have we learned?

被引:36
作者
Krammer, Florian [1 ,2 ,3 ]
机构
[1] Icahn Sch Med Mt Sinai, Dept Microbiol, New York, NY 10029 USA
[2] Icahn Sch Med Mt Sinai, Ctr Vaccine Res & Pandem Preparedness C VaRPP, New York, NY 10029 USA
[3] Icahn Sch Med Mt Sinai, Dept Pathol Mol & Cell Based Med, New York, NY 10029 USA
基金
美国国家卫生研究院;
关键词
SARS-CoV-2; Vaccines; COVID-19; Pandemic; Coronavirus; MESSENGER-RNA VACCINES; INFLUENZA-B VIRUS; ANTIBODY-RESPONSES; SARS-COV-2; CORONAVIRUS; VACCINATION; PROTECTION; IMMUNOGENICITY; SAFETY; YIELD;
D O I
10.1007/s00281-023-00996-2
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged late in 2019 and caused the coronavirus disease 2019 (COVID-19) pandemic that has so far claimed approximately 20 million lives. Vaccines were developed quickly, became available in the end of 2020, and had a tremendous impact on protection from SARS-CoV-2 mortality but with emerging variants the impact on morbidity was diminished. Here I review what we learned from COVID-19 from a vaccinologist's perspective.
引用
收藏
页码:451 / 468
页数:18
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