Recent Trends in Nanomaterial Based Electrochemical Sensors for Drug Detection: Considering Green Assessment

被引:7
作者
Ozer, Tugba [1 ,2 ]
Henry, Charles S. [3 ,4 ,5 ]
机构
[1] Yildiz Tech Univ, Fac Chem Met Engn, Dept Bioengn, TR-34220 Istanbul, Turkiye
[2] Hlth Biotechnol Joint Res & Applicat Ctr Excellenc, TR-34220 Istanbul, Turkiye
[3] Colorado State Univ, Dept Chem, Ft Collins, CO 80523 USA
[4] Colorado State Univ, Sch Biomed Engn, Ft Collins, CO 80523 USA
[5] Chulalongkorn Univ, Met & Mat Sci Res Inst, Bangkok, Thailand
关键词
Nanomaterial; Drug; Electrochemical sensors; Green assessment; Pharmaceuticals; Green synthesis; GLASSY-CARBON ELECTRODE; DICLOFENAC SODIUM; MORPHINE; NANOCOMPOSITE; NANOPARTICLES; COMPOSITES; SAFINAMIDE; IRINOTECAN; DOPAMINE; SAFETY;
D O I
10.2174/0115680266286981240207053402
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
An individual's therapeutic drug exposure level is directly linked to corresponding clinical effects. Rapid, sensitive, inexpensive, portable and reliable devices are needed for diagnosis related to drug exposure, treatment, and prognosis of diseases. Electrochemical sensors are useful for drug monitoring due to their high sensitivity and fast response time. Also, they can be combined with portable signal read-out devices for point-of-care applications. In recent years, nanomaterials such as carbon-based, carbon-metal nanocomposites, noble nanomaterials have been widely used to modify electrode surfaces due to their outstanding features including catalytic abilities, conductivity, chemical stability, biocompatibility for development of electrochemical sensors. This review paper presents the most recent advances about nanomaterials-based electrochemical sensors including the use of green assessment approach for detection of drugs including anticancer, antiviral, anti-inflammatory, and antibiotics covering the period from 2019 to 2023. The sensor characteristics such as analyte interactions, fabrication, sensitivity, and selectivity are also discussed. In addition, the current challenges and potential future directions of the field are highlighted.
引用
收藏
页码:952 / 972
页数:21
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