The Dynamics of Histone Modifications during Mammalian Zygotic Genome Activation

被引：7

作者：

Sotomayor-Lugo, Francisco ^{[1
]}

Iglesias-Barrameda, Nataly ^{[1
]}

Castillo-Aleman, Yandy Marx ^{[1
]}

Casado-Hernandez, Imilla ^{[1
]}

Villegas-Valverde, Carlos Agustin ^{[1
]}

Bencomo-Hernandez, Antonio Alfonso ^{[1
]}

Ventura-Carmenate, Yendry ^{[1
]}

Rivero-Jimenez, Rene Antonio ^{[1
]}

机构：

[1] Abu Dhabi Stem Cells Ctr, POB 4600, Abu Dhabi, U Arab Emirates

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2024年 / 25卷 / 03期

关键词：

histone modifications; chromatin landscape; mammals; embryonic development; embryonic stem cells; BIASES CELL FATE; DNA METHYLATION; EPIGENETIC REGULATION; LINEAGE COMMITMENT; DISTINCT FEATURES; H3K36; METHYLATION; VARIANT MACROH2A; GENE-EXPRESSION; MOUSE OOCYTES; STEM-CELLS;

D O I：

10.3390/ijms25031459

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mammalian fertilization initiates the reprogramming of oocytes and sperm, forming a totipotent zygote. During this intricate process, the zygotic genome undergoes a maternal-to-zygotic transition (MZT) and subsequent zygotic genome activation (ZGA), marking the initiation of transcriptional control and gene expression post-fertilization. Histone modifications are pivotal in shaping cellular identity and gene expression in many mammals. Recent advances in chromatin analysis have enabled detailed explorations of histone modifications during ZGA. This review delves into conserved and unique regulatory strategies, providing essential insights into the dynamic changes in histone modifications and their variants during ZGA in mammals. The objective is to explore recent advancements in leading mechanisms related to histone modifications governing this embryonic development phase in depth. These considerations will be useful for informing future therapeutic approaches that target epigenetic regulation in diverse biological contexts. It will also contribute to the extensive areas of evolutionary and developmental biology and possibly lay the foundation for future research and discussion on this seminal topic.

引用

页数：24

共 50 条

[11] The establishment of the 3D genome structure during zygotic genome activation [J].

Sivkina, Anastasiia L. ;

Iarovaia, Olga V. ;

Razin, Sergey V. ;

Ulianov, Sergey V. .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 2025, 1545 (01) :38-51

[12] Resetting histone modifications during human parental-to-zygotic transition [J].

Xia, Weikun ;

Xu, Jiawei ;

Yu, Guang ;

Yao, Guidong ;

Xu, Kai ;

Ma, Xueshan ;

Zhang, Nan ;

Liu, Bofeng ;

Li, Tong ;

Lin, Zili ;

Chen, Xia ;

Li, Lijia ;

Wang, Qiujun ;

Shi, Dayuan ;

Shi, Senlin ;

Zhang, Yile ;

Song, Wenyan ;

Jin, Haixia ;

Hu, Linli ;

Bu, Zhiqin ;

Wang, Yang ;

Na, Jie ;

Xie, Wei ;

Sun, Ying-Pu .

SCIENCE, 2019, 365 (6451) :353-+

[13] Role of histone methylation in zygotic genome activation in the preimplantation mouse embryo [J].

Shao, Gen-Bao ;

Ding, Hong-Mei ;

Gong, Ai-Hua .

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 2008, 44 (3-4) :115-120

[14] Role of histone methylation in zygotic genome activation in the preimplantation mouse embryo [J].

Gen-Bao Shao ;

Hong-Mei Ding ;

Ai-Hua Gong .

In Vitro Cellular & Developmental Biology - Animal, 2008, 44 :115-120

[15] Mechanisms regulating zygotic genome activation [J].

Schulz, Katharine N. ;

Harrison, Melissa M. .

NATURE REVIEWS GENETICS, 2019, 20 (04) :221-234

[16] A developmentally programmed splicing failure contributes to DNA damage response attenuation during mammalian zygotic genome activation [J].

Wyatt, Christopher D. R. ;

Pernaute, Barbara ;

Gohr, Andre ;

Miret-Cuesta, Marta ;

Goyeneche, Lucia ;

Rovira, Quirze ;

Salzer, Marion C. ;

Boke, Elvan ;

Bogdanovic, Ozren ;

Bonnal, Sophie ;

Irimia, Manuel .

SCIENCE ADVANCES, 2022, 8 (15)

[17] Dynamics of TET family expression in porcine preimplantation embryos is related to zygotic genome activation and required for the maintenance of NANOG [J].

Lee, Kiho ;

Hamm, Jennifer ;

Whitworth, Kristin ;

Spate, Lee ;

Park, Kwang-wook ;

Murphy, Clifton N. ;

Prather, Randall S. .

DEVELOPMENTAL BIOLOGY, 2014, 386 (01) :86-95

[18] Zygotic Genome Activation in Vertebrates [J].

Jukam, David ;

Shariati, S. Ali M. ;

Skotheim, Jan M. .

DEVELOPMENTAL CELL, 2017, 42 (04) :316-332

[19] The timing of zygotic genome activation [J].

Palfy, Mate ;

Joseph, Shai R. ;

Vastenhouw, Nadine L. .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 2017, 43 :53-60

[20] Methylation dynamics during the maternal-to-zygotic genome transition in dioecious species [J].

Silva, Willian T. A. F. .

PLOS ONE, 2018, 13 (07)

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