The Treatment of Diffuse Large B-Cell Lymphoma (Triple Expression) Involving the Breast, Spleen , and Bone in a Male Patient with Viral Hepatitis B: A Rare Case Report 

被引:0
作者
Zhou, Weiling [1 ]
Gao, Qian [1 ]
Wang, Lianjing [2 ]
Li, Weijing [2 ]
He, Cuiying [2 ]
Li, Yanting [3 ]
Feng, Lei [1 ]
Liu, Wei [2 ]
Liu, Lihong [2 ]
Wang, Yuan [1 ]
机构
[1] Hebei Med Univ, Hosp 4, Dept Endocrine & Metab Dis, Shijiazhuang 050000, Hebei, Peoples R China
[2] Hebei Med Univ, Hosp 4, Dept Hematol, Shijiazhuang 050000, Hebei, Peoples R China
[3] Hebei Med Univ, Hosp 2, Dept Glandular Surg, Shijiazhuang 050000, Hebei, Peoples R China
来源
CANCER MANAGEMENT AND RESEARCH | 2023年 / 15卷
关键词
breast; viral hepatitis B; diffuse large B-cell lymphoma; triple expression; autologous stem cell transplantation;
D O I
10.2147/CMAR.S427217
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: Diffuse large B-cell lymphoma (DLBCL) involving the breast, spleen, and bone in a male patient with hepatitis B virus (HBV) infection is extremely rare in clinical practice.Case Presentation: We report a case of DLBCL involving the breast, spleen, and bone (triple expression of Bcl-2+, Bcl-6+, and 70% positive C-mcy) in a male patient with HBV admitted to our hospital. The patient was treated with EPOCHx4, lenalidomide +EPOCHx2 chemotherapy, intermittent methotrexate intrathecal injections to prevent central invasion, and autologous stem cell transplantation (ASCT). The patient is currently in complete remission, and the follow-up time was 43 months.Conclusion: A patient with DLBCL involving the breast, spleen, and bone can be treated with a combination of multiple regimens. If the patient's economic conditions permit it, ASCT can be considered.
引用
收藏
页码:983 / 988
页数:6
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