Structure, function, and evolution of the metal-binding domain in the nucleosome

被引：0
|
作者：
Saavedra, Raul A. [1 ]
机构：
[1] 5525 Englishman Pl, Rockville, MD 20852 USA
来源：
BIOESSAYS | 2023年 / 45卷 / 05期
关键词：
divalent metal ions; evolution; metal-binding domain; nucleosomes; structure; function; CORE PARTICLE; HISTONES; NICKEL(II);
D O I：
10.1002/bies.202200192
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The eukaryotic nucleosome, the basic unit of chromatin, is thermodynamically stable and plays critical roles in the cell, including the maintenance of DNA topology and regulation of gene expression. At its C2 axis of symmetry, the nucleosome exhibits a domain that can coordinate divalent metal ions. This article discusses the roles of the metal-binding domain in the nucleosome structure, function, and evolution.
引用
收藏
页数：4
相关论文
共 50 条
  • [21] Insect microRNAs: Structure, function and evolution
    Behura, Susanta K.
    INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2007, 37 (01) : 3 - 9
  • [22] Nickel Binding and [NiFe]-Hydrogenase Maturation by the Metallochaperone SlyD with a Single Metal-Binding Site in Escherichia coli
    Kaluarachchi, Harini
    Altenstein, Matthias
    Sugumar, Sonia R.
    Balbach, Jochen
    Zamble, Deborah B.
    Haupt, Caroline
    JOURNAL OF MOLECULAR BIOLOGY, 2012, 417 (1-2) : 28 - 35
  • [23] Dynamic New World: Refining Our View of Protein Structure, Function and Evolution
    Mannige, Ranjan V.
    PROTEOMES, 2014, 2 (01) : 128 - 153
  • [24] Conservation among HSP60 sequences in relation to structure, function, and evolution
    Brocchieri, L
    Karlin, S
    PROTEIN SCIENCE, 2000, 9 (03) : 476 - 486
  • [25] The Role of Side Chains in the Fine-Tuning of the Metal-Binding Ability of Multihistidine Peptides
    Szekely, Eniko
    Csire, Gizella
    Balogh, Bettina Diana
    Erdei, Judit Zsuzsa
    Kiraly, Judit Maria
    Kocsi, Judit
    Pinkoczy, Julia
    Varnagy, Katalin
    MOLECULES, 2022, 27 (11):
  • [26] Metal-binding proteins and cross-linking in the defensive glue of the slug Arion subfuscus
    Christoforo, Courtney
    Fleming, Beth
    Zeitler, Matthew
    Haws, Haley
    Smith, Andrew M.
    JOURNAL OF THE ROYAL SOCIETY INTERFACE, 2022, 19 (196)
  • [27] Quantifying structural relationships of metal-binding sites suggests origins of biological electron transfer
    Bromberg, Yana
    Aptekmann, Ariel A.
    Mahlich, Yannick
    Cook, Linda
    Senn, Stefan
    Miller, Maximillian
    Nanda, Vikas
    Ferreiro, Diego U.
    Falkowski, Paul G.
    SCIENCE ADVANCES, 2022, 8 (02):
  • [28] Correlating Structure and Function of Metal Nanoparticles for Catalysis
    Zhang, Liang
    Anderson, Rachel M.
    Crooks, Richard M.
    Henkelman, Graeme
    SURFACE SCIENCE, 2015, 640 : 65 - 72
  • [29] Designing a metal-binding site in the scaffold of Escherichia coli KDO8PS
    Oliynyk, Z
    Briseño-Roa, L
    Janowitz, T
    Sondergeld, T
    Fersht, AR
    PROTEIN ENGINEERING DESIGN & SELECTION, 2004, 17 (04) : 383 - 390
  • [30] Structure and function of the Orc1 BAH-nucleosome complex
    De Ioannes, Pablo
    Leon, Victor A.
    Kuang, Zheng
    Wang, Miao
    Boeke, Jef D.
    Hochwagen, Andreas
    Armache, Karim-Jean
    NATURE COMMUNICATIONS, 2019, 10 (1)
12345