The challenges of chronic pain and fatigue

被引：40
作者：
Eccles, Jessica A. [1 ,2 ,3 ]
Davies, Kevin A. [4 ,5 ]
机构：
[1] Brighton & Sussex Med Sch, Liaison Psychiat, Falmer, England
[2] Brighton & Sussex Univ Hosp NHS Trust, Brighton, E Sussex, England
[3] Sussex Partnership Fdn NHS Trust, Brighton, E Sussex, England
[4] Brighton & Sussex Med Sch, Falmer, England
[5] Advisory Comm Clin Excellence Awards ACCEA, Leeds, W Yorkshire, England
来源：
CLINICAL MEDICINE | 2021年 / 21卷 / 01期
关键词：
pain; fatigue; fibromyalgia; hypermobility; rheumatology; EHLERS-DANLOS-SYNDROME; JOINT HYPERMOBILITY; FIBROMYALGIA; DIAGNOSIS; INTEROCEPTION; DYSFUNCTION; MANAGEMENT; EMOTION; IMPACT;
D O I：
10.7861/clinmed.2020-1009
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In this review, we explore the challenges of chronic pain and fatigue in clinical practice. Both pain and fatigue are common, troubling and frequently overlapping symptoms, and we describe both the clinical burden and the 'clinical problem'. We explore commonly associated symptoms and possible pathological associations, including variant connective tissue (joint hypermobility), small fibre neuropathy, mast cell activation, dysregulated inflammatory and interoceptive processes, which may inform treatment targets. We suggest a multidisciplinary management approach.
引用
收藏
页码：19 / 27
页数：9
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