Outcome heterogeneity of TP53-mutated myeloid neoplasms and the role of allogeneic hematopoietic cell transplantation

被引:8
作者
Pasca, Sergiu [1 ]
Haldar, Saurav D. [1 ]
Ambinder, Alexander [1 ]
Webster, Jonathan A. [1 ]
Jain, Tania [1 ]
Dalton, W. Brian [1 ]
Prince, Gabrielle T. [1 ]
Ghiaur, Gabriel [1 ]
Dezern, Amy E. [1 ]
Gojo, Ivana [1 ]
Smith, B. Douglas [1 ]
Karantanos, Theodoros [1 ]
Schulz, Cory [1 ]
Stokvis, Kristin [1 ]
Levis, Mark J. [1 ]
Jones, Richard J. [1 ]
Gondek, Lukasz P. [1 ]
机构
[1] Johns Hopkins Univ, Sidney Kimmel Comprehens Canc Ctr, Div Hematol Malignancies, Baltimore, MD 21218 USA
关键词
LEUKEMIA; MUTATIONS; IMPACT;
D O I
10.3324/haematol.2023.283886
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:948 / 952
页数:5
相关论文
共 15 条
[1]   Implications ofTP53allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes [J].
Bernard, Elsa ;
Nannya, Yasuhito ;
Hasserjian, Robert P. ;
Devlin, Sean M. ;
Tuechler, Heinz ;
Medina-Martinez, Juan S. ;
Yoshizato, Tetsuichi ;
Shiozawa, Yusuke ;
Saiki, Ryunosuke ;
Malcovati, Luca ;
Levine, Max F. ;
Arango, Juan E. ;
Zhou, Yangyu ;
Sole, Francesc ;
Cargo, Catherine A. ;
Haase, Detlef ;
Creignou, Maria ;
Germing, Ulrich ;
Zhang, Yanming ;
Gundem, Gunes ;
Sarian, Araxe ;
van de Loosdrecht, Arjan A. ;
Jadersten, Martin ;
Tobiasson, Magnus ;
Kosmider, Olivier ;
Follo, Matilde Y. ;
Thol, Felicitas ;
Pinheiro, Ronald F. ;
Santini, Valeria ;
Kotsianidis, Ioannis ;
Boultwood, Jacqueline ;
Santos, Fabio P. S. ;
Schanz, Julie ;
Kasahara, Senji ;
Ishikawa, Takayuki ;
Tsurumi, Hisashi ;
Takaori-Kondo, Akifumi ;
Kiguchi, Toru ;
Polprasert, Chantana ;
Bennett, John M. ;
Klimek, Virginia M. ;
Savona, Michael R. ;
Belickova, Monika ;
Ganster, Christina ;
Palomo, Laura ;
Sanz, Guillermo ;
Ades, Lionel ;
Della Porta, Matteo Giovanni ;
Smith, Alexandra G. ;
Werner, Yesenia .
NATURE MEDICINE, 2020, 26 (10) :1549-+
[2]   Cytogenetics and gene mutations influence survival in older patients with acute myeloid leukemia treated with azacitidine or conventional care [J].
Doehner, Hartmut ;
Dolnik, Anna ;
Tang, Lin ;
Seymour, John F. ;
Minden, Mark D. ;
Stone, Richard M. ;
Bernal del Castillo, Teresa ;
Al-Ali, Haifa Kathrin ;
Santini, Valeria ;
Vyas, Paresh ;
Beach, C. L. ;
MacBeth, Kyle J. ;
Skikne, Barry S. ;
Songer, Steve ;
Tu, Nora ;
Bullinger, Lars ;
Dombret, Herve .
LEUKEMIA, 2018, 32 (12) :2546-2557
[3]   Donor cell leukemia arising from clonal hematopoiesis after bone marrow transplantation [J].
Gondek, L. P. ;
Zheng, G. ;
Ghiaur, G. ;
DeZern, A. E. ;
Matsui, W. ;
Yegnasubramanian, S. ;
Lin, M-T ;
Levis, M. ;
Eshleman, J. R. ;
Varadhan, R. ;
Tucker, N. ;
Jones, R. ;
Gocke, C. D. .
LEUKEMIA, 2016, 30 (09) :1916-1920
[4]   Impact of Conditioning Intensity of Allogeneic Transplantation for Acute Myeloid Leukemia With Genomic Evidence of Residual Disease [J].
Hourigan, Christopher S. ;
Dillon, Laura W. ;
Gui, Gege ;
Logan, Brent R. ;
Fei, Mingwei ;
Ghannam, Jack ;
Li, Yuesheng ;
Licon, Abel ;
Alyea, Edwin P. ;
Bashey, Asad ;
Deeg, H. Joachim ;
Devine, Steven M. ;
Fernandez, Hugo F. ;
Giralt, Sergio ;
Hamadani, Mehdi ;
Howard, Alan ;
Maziarz, Richard T. ;
Porter, David L. ;
Scott, Bart L. ;
Warlick, Erica D. ;
Pasquini, Marcelo C. ;
Horwitz, Mitchell E. .
JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (12) :1273-+
[5]   Post-Transplantation Cyclophosphamide-Based Graft- versus-Host Disease Prophylaxis with Nonmyeloablative Conditioning for Blood or Marrow Transplantation for Myelofibrosis [J].
Jain, Tania ;
Tsai, Hua-Ling ;
DeZern, Amy E. ;
Gondek, Lukasz P. ;
Elmariah, Hany ;
Bolanos-Meade, Javier ;
Luznik, Leonido ;
Fuchs, Ephraim ;
Ambinder, Richard ;
Gladstone, Douglas E. ;
Imus, Philip ;
Webster, Jonathan ;
Prince, Gabrielle ;
Ghiaur, Gabriel ;
Smith, B. Douglas ;
Ali, Syed Abbas ;
Ambinder, Alexander ;
Dalton, William B. ;
Gocke, Christian B. ;
Huff, Carol Ann ;
Gojo, Ivana ;
Swinnen, Lode ;
Wagner-Johnston, Nina ;
Borrello, Ivan ;
Varadhan, Ravi ;
Levis, Mark ;
Jones, Richard J. .
TRANSPLANTATION AND CELLULAR THERAPY, 2022, 28 (05) :259.e1-259.e11
[6]   TP53 mutations in myeloid malignancies are either homozygous or hemizygous due to copy number-neutral loss of heterozygosity or deletion of 17p [J].
Jasek, M. ;
Gondek, L. P. ;
Bejanyan, N. ;
Tiu, R. ;
Huh, J. ;
Theil, K. S. ;
O'Keefe, C. ;
McDevitt, M. A. ;
Maciejewski, J. P. .
LEUKEMIA, 2010, 24 (01) :216-219
[7]   Prognostic Mutations in Myelodysplastic Syndrome after Stem-Cell Transplantation [J].
Lindsley, R. C. ;
Saber, W. ;
Mar, B. G. ;
Redd, R. ;
Wang, T. ;
Haagenson, M. D. ;
Grauman, P. V. ;
Hu, Z. -H. ;
Spellman, S. R. ;
Lee, S. J. ;
Verneris, M. R. ;
Hsu, K. ;
Fleischhauer, K. ;
Cutler, C. ;
Antin, J. H. ;
Neuberg, D. ;
Ebert, B. L. .
NEW ENGLAND JOURNAL OF MEDICINE, 2017, 376 (06) :536-547
[8]   Impact of diagnostic genetics on remission MRD and transplantation outcomes in older patients with AML [J].
Murdock, H. Moses ;
Kim, Haesook T. ;
Denlinger, Nathan ;
Vachhani, Pankit ;
Hambley, Bryan ;
Manning, Bryan S. ;
Gier, Shannon ;
Cho, Christina ;
Tsai, Harrison K. ;
McCurdy, Shannon ;
Ho, Vincent T. ;
Koreth, John ;
Soiffer, Robert J. ;
Ritz, Jerome ;
Carroll, Martin P. ;
Vasu, Sumithira ;
Perales, Miguel-Angel ;
Wang, Eunice S. ;
Gondek, Lukasz P. ;
Devine, Steven ;
Alyea, Edwin P., III ;
Lindsley, R. Coleman ;
Gibson, Christopher J. .
BLOOD, 2022, 139 (24) :3546-3557
[9]   Genomic Classification and Prognosis in Acute Myeloid Leukemia [J].
Papaemmanuil, Elli ;
Gerstung, Moritz ;
Bullinger, Lars ;
Gaidzik, Verena I. ;
Paschka, Peter ;
Roberts, Nicola D. ;
Potter, Nicola E. ;
Heuser, Michael ;
Thol, Felicitas ;
Bolli, Niccolo ;
Gundem, Gunes ;
Van Loo, Peter ;
Martincorena, Inigo ;
Ganly, Peter ;
Mudie, Laura ;
McLaren, Stuart ;
O'Meara, Sarah ;
Raine, Keiran ;
Jones, David R. ;
Teague, Jon W. ;
Butler, Adam P. ;
Greaves, Mel F. ;
Ganser, Arnold ;
Doehner, Konstanze ;
Schlenk, Richard F. ;
Doehner, Hartmut ;
Campbell, Peter J. .
NEW ENGLAND JOURNAL OF MEDICINE, 2016, 374 (23) :2209-2221
[10]   Outcomes in Patients with Poor-Risk Cytogenetics with or without TP53 Mutations Treated with Venetoclax and Azacitidine [J].
Pollyea, Daniel A. ;
Pratz, Keith W. ;
Wei, Andrew H. ;
Pullarkat, Vinod ;
Jonas, Brian A. ;
Recher, Christian ;
Babu, Sunil ;
Schuh, Andre C. ;
Dail, Monique ;
Sun, Yan ;
Potluri, Jalaja ;
Chyla, Brenda ;
DiNardo, Courtney D. .
CLINICAL CANCER RESEARCH, 2022, 28 (24) :5272-5279