Recent progress in hair follicle stem cell markers and their regulatory roles

被引:2
|
作者
Xing, Yi-Zhan [1 ]
Guo, Hai-Ying [1 ]
Xiang, Fei [2 ]
Li, Yu-Hong [1 ]
机构
[1] Army Med Univ, Dept Cell Biol, 30 Gaotanyan St, Chongqing 400038, Peoples R China
[2] Army Med Univ, Southwest Hosp, Inst Burn Res, Chongqing 400038, Peoples R China
来源
WORLD JOURNAL OF STEM CELLS | 2024年 / 16卷 / 02期
基金
中国国家自然科学基金;
关键词
Hair follicle stem cells; Bulge; Secondary hair germ; Marker; Single-cell RNA-sequencing; OUTER ROOT SHEATH; TRANSCRIPTIONAL GOVERNANCE; BIOCHEMICALLY DISTINCT; BULGE; SKIN; EXPRESSION; RUNX1; QUIESCENCE; NICHE; WNT;
D O I
10.4252/wjsc.v16.i2.126
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Hair follicle stem cells (HFSCs) in the bulge are a multipotent adult stem cell population. They can periodically give rise to new HFs and even regenerate the epidermis and sebaceous glands during wound healing. An increasing number of biomarkers have been used to isolate, label, and trace HFSCs in recent years. Considering more detailed data from single-cell transcriptomics technology, we mainly focus on the important HFSC molecular markers and their regulatory roles in this review.
引用
收藏
页码:126 / 136
页数:12
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